Background & Aim: Lumbar spinal stenosis (LSS) is a common condition. This congenital or acquired stenosis has multiple etiologies. The goal of this study was to describe intraoperative pathoanatomic findings of lumbar spinal stenosis observed within a black African population. Methods & Materials/Patients: It was a retrospective and descriptive study performed at Departmental Teaching Hospital...

Background and objectives: Resveratrol(3,5,4′-trihydroxy-trans-stilbene) is a natural polyphenole phytoalexin which exerts potential cardioprotective effects, but the cellular and molecular mechanisms responsible for these effects are still unknown. Cardiac renin angiotensin system (RAS) over-activation plays an important role in pathogenesis of left ventricula...

Buckwheat rutin has been found to be able to inhibit angiotensin II (AngII) - induced hypertrophy in cultured neonatal rat cardiomyocytes, but the mechanism remains uncertain. In this study, myocardial hypertrophy model was made by adding AngII to the medium of cardiac myocytes of neonatal rats, meanwhile, different concentrations of buckwheat rutin were applied to observe their effects. Intrac...

background nasal septal deviation (nsd) can cause upper airway obstruction, which results in hypoxia and therefore, pulmonary vasoconstriction, ventricular hypertrophy and right-sided heart failure. objectives the aim of this study is to determine the mean pulmonary arterial pressure (mpap) of the patients with nsd and the effect of septoplasty on pulmonary arterial pressure. patients and metho...

case presentation an 85 years old patient presented because of intractable right leg pain with minimal activities. she was diagnosed with significant right foraminal stenosis and she failed conservative non-invasive therapies. conclusions percutaneous lumbar hydro decompression can be a promising method for the treatment of the patients with lumbar spinal stenosis and neurogenic claudication se...

LIM-domain proteins have been shown to be associated with heart development and diseases. Systematic studies of LIM family members at the genome-wide level, which are crucial further understand their functions in cardiac hypertrophy, currently lacking. Here, 70 genes were identified characterised mice. The expression patterns differ greatly during case hypertrophy. Both Crip2 Xirp2 differential...

Hypertrophic cardiomyopathy (HCM) is a heterogeneous myocardial disease characterized by hypertrophy, mechanical and electrical activity obstacles. This study aimed to explore the relationship between YAP2 (Yes-associated protein 2) HCM clarify signaling path about pathogenesis of HCM. Our confirms that can promote cell hypertrophy at molecular level (myocardial lineage H9C2), organ (clinical s...

Background: There is conflicting data about prognostic implication of electrocardiographic (ECG) left ventricular hypertrophy (LVH) in patients with first non- ST-segment elevation myocardial infarction (NSTEMI). We aimed to examine the association of left ventricular hypertrophy (LVH) on admission electrocardiogram with adverse outcomes in patients with NSTEMI. Methods: In the present study, ...