We used a previously reported agarose-gel electrophoresis system to study the lipoprotein patterns in patients with type 3 hyperlipoproteinemia. All samples from 20 subjects tested revealed the presence of two bands with beta-lipoprotein mobility, irrespective of quantitative changes in plasma lipids induced by diet or by the administration of drugs. If these observations are confirmed, the met...

Diet is the first line of therapy for hypercholesterolemia. The major dietary factors raising the plasma cholesterol are saturated fatty acids, cholesterol, and excess total calories. For almost all forms of hyperlipidemia, the first principle of dietary therapy is to reduce saturated fatty acids, decrease cholesterol, and curtail excess calories. In patients with severe hypercholesterolemia, m...

Case Description- An eight-year-old Holstein cow with inflammed and abnormal lefteyelid was referred to the veterinary clinic of Shahid Bahonar University of Kerman.Treatment and Outcome- Because of involvement of all structures of the eye, exentrationwas done and abnormal tissues sent for histopathologic examination. Microscopicevaluations revealed mononuclear histiocytes filled with lipid in ...

A kindred with apolipoprotein E deficiency and a truncated lower molecular weight apoE mutant, designated a p 0 E 3 ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ , has been identified. Gel electrophoresis demonstrated complete absence of the normal apoE isoproteins and the presence of a small quantity of a lower molecular weight apoE. Plasma apoE levels in the proband were approximately 4% of normal. This marked deficie...

Reviewing our five-year experience with more than 1000 lipid profiles (assays for cholesterol and triglycerides In plasma of fasting patients and lipoprotein electrophoresis of their plasma lipoproteins), I conclude that lipoprotein electrophoresis is superfluous for routine clinical laboratory use, being generally redundant to the other parts of the profile. This conclusion is also prompted in...