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UNLABELLED Insulin resistance is a major component of metabolic syndrome, type 2 Diabetes Mellitus (T2DM) and coronary artery disease (CAD). Although important in T2DM, its role as a predictor of CAD in non-diabetic patients is less studied. In the present study, we aimed to evaluate the association of HOMA-IR with significant CAD, determined by coronary angiography in non-obese, non-T2DM patie...
OBJECTIVE To study white blood cells count (WBC) in women suffering from PCOS and compare these results with age and BMI-matched healthy women. The specific aim of this study was to assess the possible correlations of WBC with the major components of PCOS, obesity, insulin resistance and hyperandrogenism. DESIGN Anthropometrical, metabolic and hormonal data were analyzed from 203 women with P...
Insulin resistance was common in patients with metabolic disorders and stroke. Former studies indicated that insulin resistance was a risk factor of stroke, coronary heart disease, and cognitive impairment. Other studies also showed that higher insulin resistance was associated with poor outcome after thrombolytic treatment of ischemic stroke. Furthermore, some preliminary studies indicated tha...
BACKGROUND Metabolic factors have been associated with liver damage in patients with non-alcoholic fatty liver disease (NAFLD). AIMS To test a new marker of adipose dysfunction, the visceral adiposity index (VAI), in NAFLD patients to assess whether or not it is associated with host factors, and to investigate a potential correlation with histological findings. METHODS One hundred and forty...
BACKGROUND To determine the factors associated with an increased risk for severe steatosis (SS) and establish the Homeostatic Model Assessment-Insulin Resistance (HOMA-IR) as a screening tool. METHODS A cross-sectional study was performed in obese children to assess the relationship between the metabolic syndrome (MetS) and glucose metabolism alterations (GMA) and the risk for severe steatosi...
Objective: The study's goals are to identify a causal connection between insulin resistance (IR) and hirsutism acne vulgaris, as well evaluate the severity of two conditions in relation rising IR. Study design: An analytical cross-sectional study Place Duration: This was conducted at Primary Health Care Corporation, Qatar from August 2021 2022. Methodology: In predetermined proforma, patient's ...
BACKGROUND Metabolic Syndrome (MS) has been correlated to breast carcinogenesis. MS is common in the general population (34%) and increases with age and body mass index. Although the link between obesity, MS and hormone related cancer incidence is now widely recognized, the molecular mechanisms at the basis of such increase are still poorly characterized. A crucial role is supposed to be played...
The impact of obesity as a systemic low-grade inflammatory process has only partially been explored. To this effect, 704 community-based school-aged children (354 obese children and 350 age-, gender-, and ethnicity-matched controls) were recruited and underwent assessment of plasma levels of fasting insulin and glucose, lipids, and a variety of proinflammatory mediators that are associated with...
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