A chronic pulmonary granulomatous reaction was associated with an almost identical clinical picture in two patients exposed to talc. In both patients lung biopsy showed the deposition of talc particles and a heavy granulomatous reaction. At the time of diagnosis the Kveim test result was negative in both patients, urinary calcium excretion was normal, and there were no extrapulmonary manifestat...

Surgical suture material is usually inert and nontoxic and causes minimal inflammation of tissue. However, foreign body reactions to various suture types can lead to granuloma, abscess, or even sinus formation. We report an elderly female who was incidentally detected to have a mass protruding from the incision site which was confirmed histopathologically a chronic granulomatous reaction to non...

Hyaluronic acid is the currently most used filler in dermatology due to its low risk of adverse events. The objective of this study is to report a case of granulomatous reaction after filling with two types of hyaluronic acid, in the perioral region and in the nasolabial folds. A female patient with rheumatoid arthritis treated with leflunomide presented onset of symptoms 30 months after fillin...

Schistosomiasis is a disease whose pathology is strongly related to the granulomatous reaction formed around parasite eggs trapped in host tissues. Studies have shown that the chronic intestinal form (INT) of this infection is associated with a variety of immunoregulatory mechanisms which lead to a diminished granulomatous reaction. Using an in vitro model of granuloma reaction, we show that im...

OBJECTIVE To assess the feasibility, safety, and outcome of laparoscopic liver resection for benign liver tumors. METHODS Fourteen patients with benign liver tumors, including 11 cases of hepatic hemangioma, 1 case of hepatic focal nodular hyperplasia, 1 case of hepatic granulomatous inflammation, and 1 case of liver cyst with hyaline degeneration and calcification underwent laparoscopic live...

Sir, The presence of a granulomatous pattern has rarely been described in cutaneous lymphomas, mycosis fungoides (MF) being the variant more frequently reported (1 – 4). The aetiology of granulomatous reactions remains unclear and its prognostic value is still disputed, although a favourable influence on outcome has been hypothesized (5). We report here the case of an 87-year-old man with nodal...

Granulomatous interstitial nephritis (GIN) is a rare manifestation of renal tuberculosis (TB). We report a case of rapidly progressive renal failure (RPRF), granulomatous inflammation of cervical lymph node and GIN as presenting manifestations of TB. Aspiration cytology of cervical lymph node showed granulomatous necrotizing inflammation with acid-fast bacilli (AFB). The renal biopsy and urine ...

Injected corticosteroids can sometimes lead to a granulomatous reaction. This is apparently also true for anabolic steroids, which are often used by bodybuilders, although we have not found any histologic report on such a phenomenon. We report a case of a granulomatous reaction in a 30-year-old male bodybuilder having undergone anabolic steroid injections. Foreign bodies typical of steroids wer...

A review of 67 cases diagnosed as granulomatous, tuberculous or fungal mastitis revealed 5 cases which were similar, clinically and histopathologically, to the new entity of granulomatous mastitis described by Kessler and Wolloch. The 5 patients were young women of childbearing age, 4 with breast lesions clinically simulating carcinoma of the breast. Histopathological examination showed granulo...

Granulomatous mastitis is a rare benign inflammatory disease of the breast with multiple etiologies such as tuberculosis, sarcoidosis, foreign body reaction, and mycotic and parasitic infections. In contrast, idiopathic granulomatous mastitis (IGM) is characterized by the presence of chronic granulomatous lobulitis in the absence of an obvious etiology. Clinically and radiologically it may mimi...