BACKGROUND The mechanism of a high-fat, low-carbohydrate ketogenic diet (KD) in alleviating drug-resistant epilepsy is unknown but may be related to systemic ketosis induced under this treatment. The need for frequent measurement of systemic ketosis, which is essential for improving maintenance of the KD in patients and for studying mechanism of the KD action, has prompted us to validate the br...

INTRODUCTION Hydrogen breath test (BT) is commonly used as a diagnostic tool for the detection of small intestine bacterial overgrowth (SIBO). It was reported that colonic methane production is far more frequent in cystic fibrosis (CF) patients than in other subjects. Therefore, measuring exclusively hydrogen in the diagnostic breath test for diagnosing SIBO might be of limited value. We aimed ...

background: reported data from developed countries showed that annually a high percentage of health budgets consume for controlling and treatment of complications in diabetes disease. early diagnosis of diabetes, education and health cares, not only prevent progress of disease and complications but also it is cost effective. methods: for gestational diabetes screening, all pregnant women attend...

There is no easy and reliable test universally accepted in clinical practice to measure fat digestion. Fat balance studies are insensitive and unpleasant for regular clinical assessment, direct measures of pancreatic function are impractical for repeated use, the “steatocrit” method is not quantitative; tubeless tests have not proved to be eVective substitutes; and clinical measures, such as st...

Breath analysis has long been recognized as a potentially attractive method for the diagnosis of several diseases. The main advantage over other diagnostic methods such as blood or urine analysis is that breath analysis is fully non-invasive, comfortable for patients and breath samples can be easily obtained. One possible future application of breath analysis may be the diagnosing and monitorin...

Although scintigraphy, a non-invasive procedure, is usually considered to be the reference technique for measuring gastric emptying in humans, several drawbacks limit its application in routine practice. Expensive equipment is required and access to a nuclear medicine department, and the use of radioactive isotopes (generally Tc and In) can produce low but significant irradiation. It is diYcult...