INTRODUCTION Circadian variability of circulating leptin levels has been well established over the last decade. However, the circadian behavior of leptin in human adipose tissue remains unknown. This also applies to the soluble leptin receptor. OBJECTIVE We investigated the ex vivo circadian behavior of leptin and its receptor expression in human adipose tissue (AT). SUBJECTS AND METHODS Vi...

Abstract Based on fieldwork with migrants and border populations in Central America the story of a young Congolese woman particular, this article discusses how research participants’ use mobile communication technology provokes redefinition ethnographic field. Increasingly popular trajectory often sets out to follow migrants, yet focus keeping touch researchers at their own initiative discretio...

BACKGROUND Studies finding higher mortality rates for patients admitted to hospital at weekends rely on routine administrative data to adjust for risk of death, but these data may not adequately capture severity of illness. We examined how rates of patient arrival at accident and emergency (A&E) departments by ambulance-a marker of illness severity-were associated with in-hospital mortality by ...

Eating chocolate in the morning or evening/at night, may differentially affect energy balance and impact body weight due to changes intake, substrate oxidation, microbiota (composition/function), circadian-related variables. In a randomized controlled trial, postmenopausal females (n = 19) had 100 g of (MC), night (EC), no (N) for 2 weeks ate any other food ad libitum. Our results show that 14 ...

Calorie restriction (CR) and fasting affect lifespan, disease susceptibility response to acute injury across multiple animal models, including ischaemic injuries such as myocardial infarction or kidney hypoxia. The cargo function of circulating extracellular vesicles (EV) respond changes in host physiology, exercise, injury, other interventions. Thus, we hypothesised that EVs induced following ...

Abstract Social scientists have long been interested in how religious beliefs and practices impact are impacted by socio-political economic processes. Most recently, scholarly attention has focused on the interplay between religiosity local actors, events, institutions. Until now, measures of relied heavily self-reports surveys, but these cannot always be safely collected tend to costly. Even w...

the islamic fast during the month of ramadan is strictly observed worldwide by millions of muslims. ramadan is the 9th month of the islamic lunar calendar and fasting during ramadan is the religious duty of all healthy adult muslims. a whole month of intermittent fasting, from dawn to dusk, every year is particular only to islam and considering that islam has over 1.5 billion followers worldwid...