Three flavone-C-glycosides-cassiaoccidentalin A (1), isovitexin (2) and isoorientin (3)-were isolated from the ethyl acetate (EtOAc) soluble fraction of the methanol crude extract of the African medicinal plant Biophytum umbraculum, This is the first report of these compounds in this plant. All compounds were identified by spectroscopic analysis and comparison with published data. Isoorientin (...

A new flavone, named crotoncaudatin (1), was isolated from the stems of Croton caudatus Geisel. var. tomentosus Hook., together with nine known analogues: 3,5,6,7,8,3',4'-heptamethoxyflavone (2), tangeretin (3), nobiletin (4), 5,6,7,4'-tetramethoxy-flavone (5), sinensetin (6), kaempferol (7), tiliroside (8), kaempferol-3-O-rutinoside (9) and rutin (10). The structures of the above compounds wer...

In a continuation of our studies on biologically active substances of the Paraguayan crude drug,"Typychd kuratir(Scoparia dulcis L.,Scrophulariaceae),1)we isolated a polyoxygenated flavone(1),which was found to exhibit cytotoxicity against human cultured cells such as HeLa 229,2)HeLa S3,3)HEp-2,4)FL,5)Chang liver6)and intestine 4077)cells. Some flavonoids have been reported to be cytotoxic to K...

Abstract Polymethoxylated flavones (PMFs), the main form of in citrus, are derived from flavone branch flavonoid biosynthesis pathway. Flavone synthases (FNSs) enzymes that catalyze synthesis flavanones. However, FNS citrus has not been characterized yet. Here, we identified two type II FNSs, designated CitFNSII-1 and CitFNSII-2, based on phylogenetics transcriptome analysis. Both recombinant C...

over the past decade, the chemical behavior of flavonoids as antioxidants has become the subject ofintense experimental research. in this paper, we use a quantum-chemical approach to shed light on thereactivity of four poly phenols, benzoic acid, vanilic acid, gallic acid and flavone . in order to establishthe most efficient theoretical methodology, different methods, either hartree—fock-based ...

We tested the effects of the flavonoid 3-methoxi-5,6,7,8-hydroxy-4’hydroxy flavone (NMHTV) isolated from shoots of non arbuscular mycorrhizal (AM) inoculated clover, and of the flavonoids 5,6,7,8-hydroxy-3-methoxy flavone (MH-1); 5,6,7,8-hydroxy-4’hydroxy flavone (MH-2); and 5,7-hydroxy-3,4’-methoxy flavone (MH-3); isolated from AM clover (Trifolium repens) shoots, on spore germination, hyphal ...