BACKGROUND Sodium thiosulfate therapy has been proposed for calcific uremic arteriolopathy and nephrogenic systemic fibrosis in hemodialysis patients. The treatment brings 3.7 g (161 mmol) of sodium. How to counterbalance this sodium load was studied. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Plasma conductivity (Cp) and mass balance index were compared for 20 sessions without thiosulfate...

The leakage of dialysate is an uncommon complication in peritoneal dialysis. Here we report a 56-year-old man with uremia on continuous ambulatory per itoneal dialysis (CAPD) presenting with acute and severe scrotal swelling. Significantly elevated blood pressure, increased abdominal girth, reduced ultraf i ltrat ion and weight gain of two kilograms developed within one day. Computed tomographi...

clarify if the spectrophotometric analysis of spent dialysate may allow the possibility to monitor the removal of β2M during HD. These results were obtained from the analyses of serum and spent dialysate samples of the 22 MHD patients (16 men, 6 women) of a previous study, where we confirmed the possibility to monitor the removal of small molecules, namely uric acid, by spectrophotometric analy...

CAPD patients given lercanidipine developed non-infective turbid peritoneal dialysis. Differential diagnosis of non-infectious cloudy peritoneal dialysate includes cellular causes (i.e. leucocyte, eosinophils, red cells and malign cells) and non-cellular causes (i.e. triglyceride and drugs) [2]. Yoshimoto et al. [1,3] reported that benidipine, manidipine, nisoldipine and nifedipine caused cloud...

OBJECTIVE To investigate the possible effects of different concentrations of ionized sodium (NaI) on peritoneal ultrafiltration (UF) rate using lactate (Lac) and lactate/bicarbonate (Lac/Bic) dialysis solutions. DESIGN Two random consecutive (after an interval of 48 hours) peritoneal equilibration tests (PETs) were performed in 13 patients (4 males and 9 females) on regular continuous ambulat...

The aim of this study was to evaluate the contribution and removal dynamics of the main fluorophores during dialysis by analyzing the spent dialysate samples to prove the hypothesis whether the fluorescence of spent dialysate can be utilized for monitoring removal of any of the protein bound uremic solute. A high performance liquid chromatography system was used to separate and quantify fluorop...