O complexo respiratório bovino (CRB) é uma afecção multifatorial, a qual pode afetar os animais de qualquer idade, tendo maior impacto em bezerras. CRB iniciado por infecção viral que facilita o surgimento pneumonia bacteriana secundária, exacerbada. Os sinais clínicos incluem anorexia, prostração, aumento temperatura 39.2°C, dispneia, sons respiratórios anormais e secreção nasal, podendo evolu...

This paper analyzes the Cramér-Rao Bound associated with the estimation of certain sparse hyper-parameters in the Sparse Bayesian Learning (SBL) framework, that crucially control the sparsity of the desired signal. The CRB is shown to exhibit saturation with respect to the number of measurements, i.e., it can be lower bounded by a non-negative quantity that does not go to zero even when the num...

In Chinese cabbage (Brassica rapa), the clubroot resistance (CR) genes Crr1 and Crr2 are effective against the mild Plasmodiophora brassicae isolate Ano-01 and the more virulent isolate Wakayama-01, but not against isolate No. 14, classified into pathotype group 3. 'Akiriso', a clubroot-resistant F(1) cultivar, showed resistance to isolate No. 14. To increase the durability of resistance, we at...

We derive Cramér–Rao bound (CRB) expressions for the range (time delay), velocity (Doppler shift), and direction of a point target using an active radar or sonar array. First, general CRB expressions are derived for a narrowband signal and array model and a space-time separable noise model that allows both spatial and temporal correlation. We discuss the relationship between the CRB and ambigui...

The Hippo signaling pathway regulates organ size and tissue homeostasis from Drosophila to mammals. At the core of the Hippo pathway is a kinase cascade extending from the Hippo (Hpo) tumor suppressor to the Yorkie (Yki) oncoprotein. The Hippo kinase cascade, in turn, is regulated by apical membrane-associated proteins such as the FERM domain proteins Merlin and Expanded (Ex), and the WW- and C...

The emergence of infections caused by antimicrobial resistant microorganisms (ARMs) is currently one of the most important challenges to public health and medicine. Though speculated to originate at least partially from the overuse of antibiotics during food animal production, we hypothesized that cattle are exposed to ARMs in the environment. In this cohort study, a herd of beef calves with no...

Many components of epithelial polarity protein complexes possess PDZ domains that are required for protein interaction and recruitment to the apical plasma membrane. Apical localization of the Crumbs (Crb) transmembrane protein requires a PDZ-mediated interaction with Pals1 (protein-associated with Lin7, Stardust, MPP5), a member of the p55 family of membrane-associated guanylate kinases (MAGUK...

BACKGROUND Aim of this study was to evaluate the correlation of inflammatory markers procalcitonin (PCT), C-reactive protein (CRP) and leukocyte count (WBC) with microbiological etiology of CAP. METHODS We enrolled 1337 patients (62 +/- 18 y, 45% f) with proven CAP. Extensive microbiological workup was performed. In all patients PCT, CRP, WBC and CRB-65 score were determined. Patients were cl...

This contribution considers the true Cramer-Rao bound CRB related to estimating the carrier phase of a noisy linearly modulated signal in the presence of encoded data symbols. Timing delay and frequency offset are assumed to be known. A general expression and computational method is derived to evaluate the CRB in the presence of codes for which a trellis diagram can be drawn (block codes, trell...

This paper analyses the estimation process for Finite Rate of Innovation (FRI) signals. The main contribution is the derivation of the well known Cramér-Rao Bound (CRB) for the estimation of signal parameters for a pulse stream. Other publications consider the estimation of the signal instead of its parameters or omit the effect of sampling. In this contribution both effect are considered and a...