The pharmacodynamic (PD) interaction between the benzodiazepine agonist midazolam and the alpha(2)-adrenergic agonist dexmedetomidine was characterized for defined measures of anesthetic action and cardiovascular and ventilatory side effects in 33 rats. For various combinations of constant plasma concentrations of midazolam (0.1-20 microg/ml) and dexmedetomidine (0.3-19 ng/ml) obtained by targe...

As the existed eye tracking devices are so complex that the restrictions on the position are too many and people have to wear special equipment, this paper introduces a novel method against eye tracking: using the five near-infrared light as the source of corneal reflex. With the help of our method, people won’t need any equipment against eye tracking. Our method is able to adapt to the natural...

AN evaluation of the corneal sensitivity is an important part of many general clinical examinations and of all ophthalmological, neurological, and otological examinations. Interest in corneal sensitivity was already alive at the beginning of the 19th century, but an exact method for measuring it was not known until von Frey (1894) introduced a method, using different calibres and lengths of hai...

A GREAT number of histological studies on corneal grafts are to be found in the current literature. In very few of these, however, has any attention been paid to the nerves. Only a few authors have used nerve stainings. The present investigation has been made with the object of seeing whether any defects in the regeneration of the corneal nerves could have to do with the clouding of the grafts....

PURPOSE Diagnosis of peripheral neuropathy (PN), which affects approximately 50% of the diabetic population, is subjective, with many patients seeking a diagnosis only after presenting with symptoms. Recently, in vivo confocal microscopy of subepithelial corneal nerve density has been promoted as a surrogate marker for early detection of PN, but imaging of corneal nerves requires sophisticated ...

Objectives: To find out the prevalence and severity of keratoconus in spring catarrh patients. Study Design: Descriptive Perspective study. Setting: OPD K.D.A Teaching Hospital Kohat. Period: March 2017 to October 2019. Material & Methods: All patients suffering from were included study after consent. Proper proforma was designed for record. Detail history taken diagnosis all properly exami...

Purpose: To evaluate ocular motility (OM) abnormalities associated with Ehlers-Danlos Syndrome (EDS). Materials and methods: In this cross-sectional observational study, patients EDS underwent a complete orthoptic examination. The following tests were performed: corneal light reflex test, stereoscopic cover OM assessment, evaluation of eye pain in different gaze positions red filter test for di...

Background & Aims: This study was carried out to determine the leading indications for corneal transplantation in Kerman province. Methods: Medical records of 186 patients underwent corneal transplantation during 3 years (2004-2006) in Shafa Medical Center were evaluated retrospectively. The initial diagnosis and causes of corneal grafting were recorded. Infectious keratitis (Bacterial, Fungal,...