Greenberg and associates (2, 3) in pigeon liver homogenates and was later found in a variety of bacterial species, including Clostridium cylindrosporum (4), Micrococcus aerogenes (5), and others (6). The enzyme has been purified from acetone powders of pigeon liver (7), from Micrococcus aerogenes (6), and from Clostridium cylindrosporum (8, 9). This paper describes the purification of the enzym...

The incidence of Clostridium difficile cytotoxin has been studied in 69 consecutive patients with inflammatory bowel disease complicated by severe diarrhoea or ileostomy flux during 74 admissions to hospital. The cytotoxin was identified in only four patients, all of whom had received antimicrobials. Clostridium difficle, but not cytotoxin, was identified in 10 of 43 admissions. This followed a...

Di-tri-octahedral smectite was effective in neutralizing Clostridium difficile toxins A and B as well as Clostridium perfringens enterotoxin in vitro. However, di-tri-octahedral smectite did not inhibit the growth of Clostridium difficile and Clostridium perfringens, nor did it interfere with the activity of metronidazole. Di-tri-octahedral smectite may be a useful option for the treatment of c...

Clostridium difficile associated disease is a well recognized nosocomial infection evolving as a severediarrheal illness, associated with significantly higher rates of morbidity and mortality in critically ill patients. The incidence of Clostridium difficile infection is higher and its impact is more severe in trauma patients when compared with general inpatient population. There are several po...

bacteriocins are proteinaceous antibacterial compounds that exhibit bactericidal activity against species closely related to the producer strain. the aim of this research was to investigate the production of bacteriocin by bacillus spp. isolated from intestinal bacterial flora of the caspian frisian roach (rutilus frisii kutum). a bacteriocin produced by the bacterium bacillus cereus strain rf ...

Clostridium botulinum is a spore-forming bacterium that can produce a very powerful neurotoxin that causes botulism. In this study, we have investigated the Fur transcription regulators in Clostridium botulinum and Fur-regulated genes in Clostridium botulinum A ATCC 3502. We found that gene loss may be the main cause leading to the different numbers of Fur transcription regulators in different ...

Evidence has accumulated indicating that the clostridia ferment glucose by means of a system similar to the Embden-Meyerhof-Parnas (EMP) pathway (Elsden, 1952). In the case of Clostridium perfringens, for instance, most of the enzymes of the EMP pathway have been demonstrated in cell free extracts (Bard and Gunsalus, 1950; Shankar and Bard, 1955). Further evidence for the operation of the EMP p...

Reactive arthritis is a rare complication of Clostridium difficile enterocolitis, especially in children. We review the 6 pediatric cases published in the English and non-English literature and discuss their clinical presentation, outcome, treatment, and pathophysiology. We also report the seventh case of Clostridium difficile reactive arthritis in a 6-year-old boy who was treated with amoxicil...

The concentration and viability of spores produced by four different strains of Clostridium chauvoei (C. feseri) grown in a modified medium for 18 days are described. The medium yielded enough viable spores for experimental work.