نتایج جستجو برای: cirrhotic nodule

تعداد نتایج: 21135  

2004
E Caturelli L Solmi M Anti S Fusilli P Roselli A Andriulli F Fornari C Del Vecchio Blanco I de Sio

Background: Because hepatic cirrhosis is a major risk factor for hepatocellular carcinoma, recent guidelines by the European Association for the Study of the Liver (EASL) on clinical management of hepatocellular carcinoma recommend periodic ultrasound surveillance of cirrhotic patients with immediate workup for nodules .1 cm; an increase in the frequency of screening is considered sufficient fo...

2017
Carlo Saitta Giuseppina Raffa Angela Alibrandi Santa Brancatelli Daniele Lombardo Gianluca Tripodi Giovanni Raimondo Teresa Pollicino

Protein induced by vitamin K absence-II (PIVKA-II) is a potential screening marker for hepatocellular carcinoma (HCC). Limited data are available about its utility in discriminating neoplastic from regenerative nodules at ultrasonography (US) evaluation in cirrhotic patients. Aim of this study was to investigate the diagnostic utility of PIVKA-II in cases showing liver nodules of uncertain diag...

Journal: :journal of research in medical sciences 0
ishrat hussain dar govt medical college srinagar j & k india muqtasid ahmed kamili govt. medical college srinagar j & k showkat hussain dar govt. medical college srinagar j & k faiz ahmed kuchaai govt. medical college srinagar j & k

sister mary joseph nodule or sister mary joseph sign refers to a palpable nodule bulging into the umbilicus as a result of metastasis of a malignant cancer in the pelvis or abdomen. a rare case of sister mary joseph nodule, manifesting as ascites, cachexia and bleeding per rectum, is presented without any primary tumor despite extensive search for the same. normal 0 false false false microsofti...

2012
Eugenio Rosado Aina Rodríguez-Vilarrupla Jorge Gracia-Sancho Montserrat Monclús Jaume Bosch Joan-Carles García-Pagán

Reduced intrahepatic nitric oxide (NO) bioavailability and increased cyclooxygenase-1 (COX-1)-derived vasoconstrictor prostanoids modulate the hepatic vascular tone in cirrhosis. We aimed at investigating the reciprocal interactions between NO and COX in the hepatic endothelium of control and cirrhotic rats. NO bioavailability (DAF-FM-DA staining), superoxide (O(2)(-)) content (DHE staining), p...

2014
Shanid Abdul Sathar Sojan George Kunnathuparambil Srijaya Sreesh Premaletha Narayanan Kattoor Ramakrishnan Vinayakumar

BACKGROUND The role of Helicobacter pylori (H. pylori) in the pathogenesis of portal hypertensive gastropathy (PHG) in cirrhotic patients is poorly defined. The aim of this study was toinvestigate the prevalence of H. pylori infection and its association with PHG in patients with liver cirrhosis. METHODS Seroprevalence of H. pylori was tested in 70 cirrhotic patients with PHG (cases) and 70 c...

2011
Abdulaziz Aldawood Yaseen Arabi Abdulrahman Aljumah Alawi Alsaadi Asgar Rishu Hasan Aldorzi Saad Alqahtani Mohammad Alsultan Afaf Felemban

BACKGROUND Cirrhotic patients are characterized by a decreased synthesis of coagulation and anticoagulation factors. The coagulopathy of cirrhotic patients is considered to be auto-anticoagulation. Our aim was to determine the incidence and predictors of venous thromboembolism (VTE) and examine the practice of deep venous thrombosis (DVT) prophylaxis among hospitalized cirrhotic patients. MET...

2013
Manale El Idrissi Valérie Hervieu Philippe Merle Franck Mortreux Eric Wattel

BACKGROUND Among the numerous genetic defects associated with hepatocarcinogenesis, telomere abnormalities appear to play a role both in tumor promotion and maintenance. Telomeres, the chromosome extremities, are protected by specific proteins, the shelterin complex and by additional factors. Besides telomerase dysregulation, expression changes of these telomere factors have been observed in ca...

Introduction: Prostate cancer is the most prevalent malignancies among males. Prostate specific antigen (PSA) is used for screening of this malignancy. Serum levels of PSA is influenced by liver function. This study evaluate variations of serum levels of PSA amongst cirrhotic patients, before and after receiving liver transplantation. Material and methods: all cirrhotic males older than 45 y...

2016
V. Isakov D. Koloda N. Tikhonova T. Kikalishvili E. Krasavina K. Lekishvili I. Malaya M. Ryska M. Samsonov V. Tolkacheva

In this study we sought to evaluate narlaprevir (NVR) pharmacokinetics (PK) after a single dose with or without ritonavir (RTV) in cirrhotic versus healthy subjects. NVR at 200 mg was administered to 8 healthy and 8 cirrhotic subjects, and NVR at 100 mg with RTV at 100 mg was administered to 8 healthy and 8 cirrhotic subjects. PK analysis was performed. The geometric mean maximum concentration ...

Journal: :Gastroenterology 2014
Atsuyuki Ikeda Takahiro Shimizu Yuko Matsumoto Yosuke Fujii Yuji Eso Tadashi Inuzuka Aya Mizuguchi Kazuharu Shimizu Etsuro Hatano Shinji Uemoto Tsutomu Chiba Hiroyuki Marusawa

BACKGROUND & AIMS Hepatocellular carcinoma develops in patients with chronic hepatitis or cirrhosis via a stepwise accumulation of various genetic alterations. To explore the genetic basis of development of hepatocellular carcinoma in hepatitis C virus (HCV)-associated chronic liver disease, we evaluated genetic variants that accumulate in nontumor cirrhotic liver. METHODS We determined the w...

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