نتایج جستجو برای: bronchodilatory

تعداد نتایج: 201  

Journal: :Journal of tropical pediatrics 2014
Y X Sun C H Gong S Liu X P Yuan L J Yin L Yan T T Shi J H Dai

OBJECTIVES To determine the response of nebulized magnesium sulfate on the lung function of acetylcholine-induced asthma children. METHODS Three hundred and thirty children of asthma with positive bronchial provocation test were randomly divided into three groups: magnesium sulfate, albuterol, and a combination of magnesium sulfate and albuterol. Lung function was compared between the three g...

2014
Ken-Ichiro Tanaka Shota Kurotsu Teita Asano Naoki Yamakawa Daisuke Kobayashi Yasunobu Yamashita Hiroshi Yamazaki Tomoaki Ishihara Hiroshi Watanabe Toru Maruyama Hidekazu Suzuki Tohru Mizushima

We recently proposed that mepenzolate bromide (mepenzolate) would be therapeutically effective against chronic obstructive pulmonary disease (COPD) due to its both anti-inflammatory and bronchodilatory activities. In this study, we examined the benefits and adverse effects associated with different routes of mepenzolate administration in mice. Oral administration of mepenzolate caused not only ...

Journal: :Journal of Drug Delivery and Therapeutics 2022

Seeds of cumin (Cuminum cyminum L.) are widely used as a spice for their distinctive aroma. C. have been in traditional medicine to treat variety diseases. Literature presents ample evidence biomedical activities which is attributed its bioactive secondary metabolites - terpenes, phenols, and flavonoids. Besides, health effects seeds experimentally validated through phytochemical analysis depic...

Journal: :iranian biomedical journal 0
محمد کاظم قریب ناصری mohammad kazem gharib naseri اکبر حیدری akbar heidari

several reports have shown the various effects of grape (vitis vinifera) seed extract such as antioxidant, hypotensive, hypolipidemic and vasodilatory effects. the aim of present study was to investigate the effect of grape leaf hydroalcoholic extract on isolated rat tracheal contractions induced by kcl and acetylcholine. the trachea was removed from male adult sprague-dawley rat and placed in ...

Journal: :Journal of ethnopharmacology 2010
Abdul Jabbar Shah Anwarul-Hassan Gilani

AIM OF THE STUDY This study was undertaken to provide a pharmacological basis for traditional use of Acorus calamus in airways disorders. MATERIALS AND METHODS Isolated guinea-pig trachea and atria were suspended in organ baths bubbled with carbogen and mechanisms were found using different parameters. RESULTS In isolated guinea-pig tracheal segments, crude extract of Acorus calamus was mor...

2014
Joan P Blonder Sarah C Mutka Xicheng Sun Jian Qiu Lucia H Green Navdeep K Mehra Ramakrishna Boyanapalli Michael Suniga Kirsten Look Chris Delany Jane P Richards Doug Looker Charles Scoggin Gary J Rosenthal

BACKGROUND S-nitrosoglutathione (GSNO) serves as a reservoir for nitric oxide (NO) and thus is a key homeostatic regulator of airway smooth muscle tone and inflammation. Decreased levels of GSNO in the lungs of asthmatics have been attributed to increased GSNO catabolism via GSNO reductase (GSNOR) leading to loss of GSNO- and NO- mediated bronchodilatory and anti-inflammatory actions. GSNOR inh...

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