Dear Editor, Translocation t(8;9)(p22;p24) has been reported in diverse hematologic neoplasms, including acute leukemia, myeloproliferative neoplasm (MPN), and myelodysplastic syndromes/myeloproliferative neoplasm. These findings indicate that the mutation occurs in pluripotent, lymphoid-myeloid stem cells [1]. The pericentriolar material 1 (PCM1) gene, located on chromosome 8p22, encodes a pro...

The in vivo response to recombinant human granulocyte-monocyte colony-stimulating factor (rHu GM-CSF) in facilitating the reconstitution of granulo-monopoiesis was evaluated in a patient with Graves’ disease who developed severe aplastic anemia during methimazole therapy. After 10 days of treatment with rHu GM-CSF, the neutrophil and monocyte counts rose to 1.65 × 10/l and 0.41 × 10/l, respecti...

results in the first series, cellularity and blood levels were significantly lower in capillary-fnb compared with cfnb (p < 0.001 and p = 0.011, respectively). there was no significant difference between cfnb and vacfnb in cellularity and blood (p = 0.15 and p = 0.1, respectively). in the second series, cellularity was significantly higher in cfnb compared with vacfnb (p < 0.001) with no signif...

Dear Editor, We describe the diagnostic characteristics of three pediatric patients with early T-cell precursor (ETP)-ALL. All three patients had hyperleukocytosis with a white blood cell (WBC) count of more than 100.0×10/L, showed immunophenotypic findings consistent with ETP-ALL, and were positive for FLT3 mutations. The clinical and laboratory findings, including immunophenotyping results (F...

Bone marrow biopsies ( 244) performed buffy coat. The greatest variance was seen with a Jamshidi needle were evaluated in the hypercellular or normocellular marin 53 children with leukemia or aplastic rows, as estimated by biopsy, in which anemia. Adequate specimens were ob39% were misinterpreted as moderately tamed in 85%. Results of cellularity estior severely hypocellular by aspirate. Volmat...

Background: Acute myeloid leukaemia in adult constitutes 80% of whole acute cases; its frequency progressively increases with age.&#x0D; Objective: To evaluation the parameters AML patients clinically and haematologically Erbil City.&#x0D; Patients Methods: A particular analysis hospital records retrospective study 29 was taken on. The cases were analyzed achieved at Nanakaly city during years ...

Introduction: Multiple sclerosis (MS) has been recognized as a common neurodegenerative disease that occurs after an&nbsp;Auto reactive&nbsp;T cells&nbsp;against myelin antigens.&nbsp; Demyelination and inflammation are the main features of this disease. The anti-inflammatory and neuroprotective roles of bone marrow-derived mesenchymal stem cells (BM-MSCs) have been considered as a suitable tre...