Case report of a patient with rheumatoid arthritis who developed severe neutropenia, splenomegaly and was diagnosed with Felty's syndrome. The patient later developed Kala-azar. Both diseases have similar clinical and laboratory presentation, making the differential diagnosis difficult. The present case report aims at drawing attention to the identification of visceral Leishmaniasis infection i...

1. Khod AS, Thompson MH. Visceral leishmaniasis contracted in the Mediterranean area. Arch Dis Child 1983; 58 : 930-931. 2. Manson Bahr PEC, A,pted FLC. Manson's Tropical Diseases. 18th edition. London : Balliare Tindall. 1982 : 93-104. 3. Cachia EA, Fenech FF. A review of kalaazar in Malta from 1947 to 1962. Trans R Soc Trop Med Hyg 1964; 58 : 234-241. 4. Ozsoylu S, Hicsonmez G. Mediterranean ...

OBJECTIVE To compare the use of generic and proprietary sodium stibogluconate for the treatment of visceral leishmaniasis (kala-azar). METHODS A total of 102 patients with confirmed kala-azar were treated in a mission hospital in West Pokot region, Kenya, with sodium stibogluconate (20 mg/kg/day for 30 days)--either as Pentostam (PSM) or generic sodium stibogluconate (SSG); 51 patients were a...

BACKGROUND Visceral leishmaniasis (VL), commonly known as kala-azar is a systemic disease caused by parasitic protozoan species of genus Leishmania and transmitted by species of Phlebotomus (sand flies). It is a poverty-related disease and associated with malnutrition, displacement, poor housing, weakness of the immune system and lack of resources. For the success of prevention and control prog...

Kala-azar as a distinct clinical entity has been recognized in this country for about a century. A number of epidemics occurred in Bengal, and though it was in early stages confused with malaria, failure to respond to specific treatment led to the establishment of its separate entity. This was confirmed in 1903 by the discovery of Leishman-Donovan bodies? the causative organism, by W. B. Leishm...

BACKGROUND Known as 'neglected disease' because relatively little effort has been applied to finding cures, leishmaniasis kills more than 150,000 people every year and debilitates millions more. Visceral leishmaniasis (VL), also called Kala Azar (KA) or black fever in India, claims around 20,000 lives every year. Whole genome analysis presents an excellent means to identify new targets for drug...

Pathogenesis in kala-azar is associated with depressed cellular immunity and significant elevation of antileishmanial antibodies. Since these antibodies are present even after cure, analysis of the parasite-specific isotypes and immunoglobulin G (IgG) subclasses in kala-azar patients may shed new light on the immune responses during progression and resolution of infection. Using leishmanial mem...

produced in man by inoculation of cultures of Leishmania tropica. Cutaneous inoculation of Leishmania donovani from spleen puncture material from a case of kala-azar, however, is reported to have ' apparently produced kala-azar in a man' but on two occasions accidental inoculation of spleen puncture material from cases of kala-azar was without any effect (Napier, 1927). Recently, Terry et al. (...

‘‘She begged pardon from us, from her child, from Allah...while she was getting down from the bed she closed her eyes, and started moaning. When we held her and made her sit on the bed, she said...Mother, I am dying, I am dying. She collapsed on my lap. We splashed water on her face. We said Doa Durud [religious verse]...then phoned my son.’’ This is how the mother-in-law of the deceased woman ...

Resumo O jogo patológico é um transtorno do controle do impulso que está ganhando mais e mais atenção. Este artigo revisa os critérios diagnósticos e os instrumentos de rastreamento para o jogo patológico, bem como os índices de prevalência desse transtorno ao redor do mundo, com ênfase na situação do jogo de azar no Brasil. Os tratamentos para o jogo patológico são também descritos, incluindo ...