نتایج جستجو برای: axlebox clearance
تعداد نتایج: 47897 فیلتر نتایج به سال:
Kumar and Birge introduce efferocytosis - the process by which dead or dying cells are engulfed and digested by phagocytes.
The majority of the human population shows a decline in renal clearance with age and a loss of renal physiologic reserve. Kidneys are increasingly less able to deal with stressful challenges such as a salt or acid load. It is not clear what underlies this aging-related change and whether it is inevitable or can be modified in such a way as to preserve renal function throughout the life span. Th...
The aim of this study was to evaluate different physiologically based modeling strategies for the prediction of human pharmacokinetics. Plasma profiles after intravenous and oral dosing were simulated for 26 clinically tested drugs. Two mechanism-based predictions of human tissue-to-plasma partitioning (P(tp)) from physicochemical input (method Vd1) were evaluated for their ability to describe ...
background: colorectal carcinoma is the third most common cause of death in iran. this study was performed in order to determine the appropriate distal clearance margin (dcm) for resection of rectal cancer in patients who undergo neoadjuvant chemoradiotherapy for sphincter preserving procedure. materials and methods: this was a cross-sectional study conducted in shahid faghihi hospital of shira...
nonlinear hunting speeds of railway vehicles running on a tangent track are analytically obtained using hopf bifurcation theory in this paper. the railway vehicle model consists of nonlinear primary yaw dampers, nonlinear flange contact stiffness as well as the clearance between the wheel flange and rail tread. linear and nonlinear critical speeds are obtained using bogoliubov method. a compreh...
Six patients with chronic renal failure (CRF group) and four healthy subjects (HS group) were given 5 mg oral and intravenous doses of bumetanide in a random, crossover design. The CRF group had significantly lower plasma and renal clearances, resulting in a five-to sixfold reduction in the fractional urinary excretion of the drug. The percent free drug in plasma for the CRF group was more than...
The effect of Positive End Expiratory Pressure (PEEP) on the hepatic elimination of low to moderate extraction ratio drugs has not been clearly defined. We prospectively investigated the effect of PEEP on the clearance of theophylline in 30 (20 males and 10 females) intubated critically ill adult patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS). The Mean (±SD) age ...
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