Ziprasidone is an atypical antipsychotic drug that is believed to have a low propensity for inducing extrapyramidal symptoms, including tardive dyskinesia (TD). Two of our patients developed TD after 23 months and 34 months of ziprasidone monotherapy, respectively. One of the patients had had earlier exposure to typical antipsychotic drugs, but no other predisposing factors for TD were noted. T...

AMA Rybakowski J. Sixty-year history of dopaminergic mechanism antipsychotic drugs. Pharmacotherapy in Psychiatry and Neurology/Farmakoterapia w Psychiatrii i Neurologii. 2023;39(1):9-17. doi:10.5114/fpn.2023.127421. APA Rybakowski, (2023). Neurologii, 39(1), 9-17. https://doi.org/10.5114/fpn.2023.127421 Chicago Janusz. 2023. "Sixty-year drugs". Neurologii 39 (1): Harvard pp.9-17. MLA drugs." v...

~ ! , -" .~ link these neuropathologic findings to pathogenic processes and the clinical dimensions of the disease. Two questions that have not been resolved, however, are 1) whether some of the neuropathologic findings associated with schizophrenia are a consequence of the disease or of the substantial treatment that most patients receive in the course of their illness and 2) whether the neuro...

Advances in the biological sciences have dramatically improved the understanding of schizophrenia and related psychotic illnesses. One of the most compelling findings is the substantial degree to which cognition is impaired in these illnesses and the remedial effects that antipsychotic drugs have in treating these cognitive impairments. Despite these promising discoveries, legal cases and schol...

EMERGENCY nurse 17 Antipsychotic drugs (or neuroleptics) are a large class of drugs which can be divided into three groups: phenothiazine, miscellaneous and atypical (Box 1). They are used to tranquillise patients without impairing consciousness and without causing paradoxical excitement. They are often referred to as major tranquillisers but this is misleading since these drugs also relieve fl...

OBJECTIVE This study examined trends in the prescription of antipsychotic drugs in a nationally representative sample of physicians in nonfederal office-based clinical practice during the 1990s. METHODS The authors analyzed physician-reported data from annual National Ambulatory Medical Care Surveys between 1989 and 1997 using weighted national estimates of physician visits during which antip...

BACKGROUND Currently a large number of atypical antipsychotics available in the market are endorsed as better option for treating schizophrenia than the typical antipsychotics. Information regarding the utilization pattern of antipsychotic drugs is lacking in Nepalese population particularly in Western Nepal. By means of this study one is expected to acquire an idea concerning clinician's prefe...

OBJECTIVES To measure the incidence of movement side effects of antipsychotic drugs in adults with intellectual disability and compare rates with adults without intellectual disability. DESIGN Cohort study using data from The Health Improvement Network. SETTING UK primary care. PARTICIPANTS Adults with intellectual disability prescribed antipsychotic drugs matched to a control group of ad...