beta-Alanine catabolism in Pseudomonas fluorescens is initiated by the enzyme beta-alanine transaminase. We have isolated mutants which fail to produce this enzyme and thus cannot grow on beta-alanine as the sole nitrogen source. The accumulation of beta-alanine-1-(14)C has been studied in one of these mutants, strain 67, and in the wild type. In the mutant, beta-alanine remains in a stable int...

Serum alanine aminotransferase (ALT) and y-glutamyltransferase (y-GT) activities were measured in over 2000 north London blood donors. The results were compared with those from the United States. The percentage of the total donor population with ALT activities above 40 IU/1 in 1986 was greater than that found in our earlier studies in 1973 and 1982 (4*6% compared with 2-8% and 3 1 % , respectiv...

BACKGROUND The current organ shortage has prompted the use of marginal organs. We conducted this retrospective study to present our experience with transplanting deceased donor livers with elevated levels of serum transaminases and to explain whether elevated levels of serum transaminases in donors affect allograft function and survival of the recipients. METHODS Data of deceased donor livers...

Measurements of alanine aminotransferase and aspartate aminotransferase with the SMAC were evaluated for correlation with the ABA-100, precision, linearity, and carryover. We assayed 200 specimens with normal and abnormal aminotransferase activities with both the SMAC (y) and the ABA-100 (X). Linear regression analysis of the data yielded the following: alanine aminotransferase (r = 0.9732, y =...

Serum alanine aminotransferase (ALT) and y-glutamyltransferase (y-GT) activities were measured in over 2000 north London blood donors. The results were compared with those from the United States. The percentage of the total donor population with ALT activities above 40 IU/l in 1986 was greater than that found in our earlier studies in 1973 and 1982 (4-6% compared with 2-8% and 3 1%, respectivel...

Asymmetric synthesis of chiral amines from prochiral ketones using transaminases is an attractive biocatalytic strategy. Nevertheless, it hampered by its unfavorable thermodynamic equilibrium. In the present work, insitu by-product removal strategy was applied for 3-amino-1-phenylbutane (3-APB) coupling a transaminase with pyruvate decarboxylase (PDC), which does not require use any expensive a...

conclusions ehp was able to both reduce ldl-ch and to significantly decrease markers of oxidative stress and lipid peroxidation induced by hyperlipidemia. therefore, this herb, as a new pharmacological component, could be used to reduce certain blood lipids, lipid peroxidation, and aminotransferase markers. materials and methods thirty-two male rats weighting 200 ± 10 g were randomly divided in...

Background The aim of the study was assessing De Ritis score, an inflammatory marker, in Hashimoto's thyroiditis (HT) patients which is characterized with autoimmunity and chronic inflammation. Methods Between October 2021 2022, subjects our outpatient clinics diagnosed healthy controls enrolled to study. Age, gender, laboratory parameters including C-reactive protein (CRP), alanine (ALT), aspa...