Spt7 belongs to the suppressor of Ty (SPT) module Spt-Ada-Gcn5-acetyltransferase (SAGA) complex and is known as yeast ortholog human STAF65γ. lacks intrinsic enzymatic activity but responsible for integrity proper assembly SAGA complex. Here, we determined role subunit in cellular aging. We found that was indispensable a normal lifespan both dividing nondividing cells. In quiescent state cells,...

will be missed. Each author must do his best, and the editor, advised by his referees, must judge whether that best is good enough. If the editor decides to publish his readers can judge and comment, either privately or in the correspondence column of the journal, if prior claims have been overlooked. They frequently do. Alzheimer's disease: recent advances and future prospects Recent years hav...

1. Various methods for the extraction of choline acetyltransferase (acetyl-CoA-choline O-acetyltransferase, EC 2.3.1.6) from immature human placenta (18-28 weeks of gestation) are described. 2. The crude enzyme was found to be stable at -18 degrees and +4 degrees under a variety of conditions. 3. Purification methods, including ammonium sulphate fractionation, gel filtration on various grades o...

304 3.5. Namboodiri. kl. A. A,. Nakai. C‘. k Klein, 1). C. (1070) J. Ncurochem. 33. 807-810 30. Klein. 1). C’. k Namboodiri, M. A. A. (1082) Trends Biochem. Sci. 7, OXI02 37. Namboodiri, M. A. A,, Weller, J. I , . Kc Klein, I). C’. (1080) J. l k l . Cheni. 255. 6032-0035 38. Namboodiri, M. A. A,. Weller, J. I, . K: Klein, I). C’. ( 1080) Hiochem. Hiophys. Kes. C’ommun. 96, 1 8%1 05 30 . Niimboo...