نتایج جستجو برای: acceptor eda interaction
تعداد نتایج: 582685 فیلتر نتایج به سال:
in this study, the interaction between no2+ cation and hen (n = 1-7) clusters is investigated by means of ab initio calculations at mp2/aug-cc-pvtz and qcisd/aug-cc-pvtz computational levels. the first and second solvation shells were obtained while n atom of no2+ interacts with five and two he atoms, respectively. stabilization energies of the studied complexes including basis set superpositio...
Ectodermal organogenesis is regulated by inductive and reciprocal signalling cascades that involve multiple signal molecules in several conserved families. Ectodysplasin-A (Eda), a tumour necrosis factor-like signalling molecule, and its receptor Edar are required for the development of a number of ectodermal organs in vertebrates. In mice, lack of Eda leads to failure in primary hair placode f...
سابقه و هدف: ترس از سوزن تزریق دندانپزشکی یکی از عوامل اصلی ترس از دندانپزشکی در کودکان است. یکی از روشهای بیحسی موضعی، بیحسی الکترونیکی دندان (EDA) است. لذا بر آن شدیم میزان تاثیر کاربرد بیحسی الکترونیکی دندان را با روش متداول بیحسی موضعی در کودکان 7 - 5 ساله مراجعه کننده به بخش کودکان دانشکده دندانپزشکی دانشگاه آزاد اسلامی تهران مقایسه کنیم. مواد و روش ها: این کارآزمایی بالینی بر روی ...
Background and Purpose—The fibronectin isoform containing the alternatively spliced extra domain A (EDA -FN) is normally absent from the circulation, but plasma levels of EDA -FN can become markedly elevated in several human pathological conditions associated with inflammation including ischemic stroke. It remains unknown whether EDA -FN contributes to stroke pathogenesis or is simply an associ...
BACKGROUND The fibronectin-splicing variant containing extra domain A (Fn-EDA) is present in negligible amounts in the plasma of healthy humans but markedly elevated in patients with comorbid conditions, including diabetes mellitus and hypercholesterolemia, which are risk factors for stroke. It remains unknown, however, whether Fn-EDA worsens stroke outcomes in such conditions. We determined th...
Glucose-induced changes of artery anatomy and function account for diabetic vascular complications, which heavily impact disease morbidity and mortality. Since fibronectin containing extra domain A (EDA + FN) is increased in diabetic vessels and participates to vascular remodeling, we wanted to elucidate whether and how EDA + FN is implicated in diabetes-induced endothelial dysfunction using is...
The perturbational treatment of H-bonded systems reduces the discussion of H-bond properties to that of proton donor and proton acceptor properties. Among the variety of interaction contributions within perturbation theory it is simply the electrostatic interaction which mainly seems to control H-bond strength and stereochemistry of H-bonds. The easy accessible classical and clear electrostatic...
BACKGROUND AND PURPOSE The fibronectin isoform containing the alternatively spliced extra domain A (EDA(+)-FN) is normally absent from the circulation, but plasma levels of EDA(+)-FN can become markedly elevated in several human pathological conditions associated with inflammation including ischemic stroke. It remains unknown whether EDA(+)-FN contributes to stroke pathogenesis or is simply an ...
Sialyltransferases are enzymes responsible for the important sialylation of glycoconjugates. Since crystal structures are not available, other tools are needed to study enzymatic mechanisms. As a model, we used human alpha2,6-sialyltransferase. A putative acceptor-binding domain containing the small and the very small sialyl motifs was randomly mutated. This resulted in enzymes with altered enz...
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