Natural ageing has a major influence on the properties of paper, while light, heat, and humidity are environmental influences that most disrupt stability paper. This research focuses changes in straw-containing papers caused by accelerated ageing. The were made laboratory mixing straw pulp with recycled fibers different weight ratios artificially aged dry-heat treatment (thermal oxidation) UV r...

We sought to use splice-switching antisense oligonucleotides to produce a model of accelerated ageing by enhancing expression of progerin, translated from a mis-spliced lamin A gene (LMNA) transcript in human myogenic cells. The progerin transcript (LMNA Δ150) lacks the last 150 bases of exon 11, and is translated into a truncated protein associated with the severe premature ageing disease, Hut...

Ageing and degradation has been accomplished on Microstructured Polymer Optical Fiber (MPOF) by changing simulated ambient environmental condition to ascertain their suitability in possible automotive application. Both single Moded Microstructured Polymer Optical Fiber (SM-MPOF) and Graded Index Microstructured Polymer Optical Fiber (GI-MPOF) has been studied for physical ageing and chemical de...

We are honoured to provide this celebratory editorial marking the 125th anniversary of the British Journal of Dermatology. Human skin, like all organs, undergoes cumulative deleterious alterations that result in a decline of function due to the passage of time. However, unlike other organs, with the exception of the eye, skin experiences cumulative damage due to ultraviolet (UV) irradiation fro...

In ageing populations many patients have multiple diseases characterised by acceleration of the normal ageing process. Better understanding of the signalling pathways and cellular events involved in ageing shows that these are characteristic of many chronic degenerative diseases, such as chronic obstructive pulmonary disease (COPD), chronic cardiovascular and metabolic diseases, and neurodegene...

Parkinson's disease is one of the most common neurodegenerative disorders of the elderly and ageing hence described to be a major risk factor. Telomere shortening as a result of the inability to fully replicate the ends of linear chromosomes is one of the hallmarks of ageing. The role of telomere dysfunction in neurological diseases and the ageing brain is not clarified and there is an ongoing ...

Seed ageing is influenced by two environmental factors, RH and temperature. The deterioration of the stored seed is a natural phenomenon and the seeds tend to lose viability even under ideal storage conditions . Autooxidation of lipids and increase in the content of free fatty acids during storage period are the main reasons for rapid deterioration of seed of oil plants. Accelerated ageing has ...

The molecular mechanisms leading to human senescence are still not known mostly because of the complexity of the process. Different research approaches are used to study ageing including studies of monogenic segmental progeroid syndromes. None of the known progerias represents true precocious ageing. Some of them, including Werner (WS), Bloom (BS), and Rothmund-Thomson syndromes (RTS) as well a...