Relative absorbed dose energy response correction, R, for various radiochromic films in water phantom is calculated by the use of the Monte Carlo-based EGSnrc code system for high energy brachytherapy sources 60Co, 137Cs, 192Ir and 169Yb. The corrections are calculated along the transverse axis of the sources (1-15 cm). The radiochromic films investigated are EBT, EBT2 (lot 020609 and lot 03110...

Simvastatin is a HMG-CoA reductase inhibitor widely used to lower plasma cholesterol and to protect against cardiovascular risk factors. The aim of this study was to investigate whether simvastatin attenuates ionizing radiation-induced damage in the mouse thymus and to elucidate the possible mechanisms invovled. For this purpose, male C57BL/6J mice aged 6 weeks were used and exposed to 4 Gy 60C...

This study was undertaken to investigate the biological effect of monoenergetic neutrons on human lymphocyte DNA and chromosomes. Monoenergetic neutrons of 2.3, 1.0, 0.79, 0.57, 0.37 and 0.186 MeV were generated, and 252Cf neutrons and 60Co gamma-rays were also used for comparison. Biological effect was evaluated two ways. The RBE values with the comet assay were estimated as 6.3 and 5.4 at 0.3...

background: high density concrete is extensively used for efficient radiation attenuation in radiotherapy rooms and nuclear reactors. over the past eight years, some efficient galena-based concrete samples for shielding x or gamma rays was produced. the goal of this study was to produce a novel high density concrete against neutron and photon radiations using tourmaline and galena. materials an...

In this study, we perform a scientific comparative analysis of using (60)Co beams in intensity-modulated radiation therapy (IMRT). In particular, we evaluate the treatment plan quality obtained with (i) 6 MV, 18 MV and (60)Co IMRT; (ii) different numbers of static multileaf collimator (MLC) delivered (60)Co beams and (iii) a helical tomotherapy (60)Co beam geometry. We employ a convex fluence m...

This paper compares the isotopes (60)Co and (192)Ir as radiation sources for high-dose-rate (HDR) afterloading brachytherapy. The smaller size of (192)Ir sources made it the preferred radionuclide for temporary brachytherapy treatments. Recently also (60)Co sources have been made available with identical geometrical dimensions. This paper compares the characteristics of both nuclides in differe...