A recent report described the expression of Fas ligand (FasL) by melanoma cells as an important mechanism involved in the immune evasion by tumors [M. Hahne et al., Science (Washington DC), 274: 1363-1366, 1996]. To investigate the expression of FasL by melanomas, we screened a panel of early-passage cell lines by functional assay and reverse transcriptase-PCR. Using conditions designed to repl...

Taylor and Francis Ltd CUS_A_136345.sgm 10.1080/00220270500363620 Journal of Curri ulum Studies 0222-0272 (p i t)/1366-5839 (online) Original Article 2 05 & Francis 0002 5 PeterJoh p .j n@ lymo th.ac.uk Rationalistic, technical curriculum planning has been the dominant model underpinning student teachers’ lesson-planning for a generation or more in England and Wales. In recent years, this proce...

A matched case-control study was conducted to investigate the risk of gastric cancer in coalminers in the southern part of Limburg, The Netherlands. All 683 male cases of gastric cancer were identified at the five pathology departments in the area, all histologically confirmed by a pathologist. For each case a control patient, free of gastric cancer, was selected from the same pathology departm...

Oxyhemoglobin is the species of hemoglobin in erythrocyte hemolysates that inhibits the diazo reaction. Ferric hemoglobin derivatives and species with relatively low molecular mass do not interfere. Conversion of oxyhemoglobin to acid hematin under assay reaction conditions is associated with rapid destruction of bilirubin, which accounts for the diazo reaction error. The most probable mechanis...

Objective: The aim of the present study is to validate a rapid and simple allelespecifi c PCR that genotypes TCF7/L2 rs7903146 (C/T) polymorphism with standard PCR instruments. Methods: Two forward primers with variations in their 3’ nucleotides were designed in such a way that each was specifi c for one of the two variants. They were combined with a common reverse primer into two PCR reactions...

eptifibatide in patients with acute coronary syndrome. N Engl J Med. 1998;339: 436-443. 23. Boersma E, Harrington RA, Moliterno DJ, et al. Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials. Lancet. 2002;359:189-198. 24. Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA 2002 guideline update for the management of patie...

Abstract Spondylometaphyseal dysplasia Algerian type (MIM no.: 184253) is an uncommon autosomal dominant skeletal caused by heterozygous mutations in the COL2A1 gene 120140). In this case based review, we reported a 5-year-old boy with short stature, severe dorsolumbar scoliosis, lumbar hyperlordosis, trunk, and genu valgum. Radiological examination showed platyspondyly, irregular metaphyseal r...