BACKGROUND Complex bidirectional relationships have been described between body weight, thyroid function, and risk of thyroid disorders, including thyroid autoimmunity. We used a life-course approach to examine the potential association of childhood or adult body weight with the risk of thyroid autoimmunity and other thyroid disorders at age 60-64 years in a large population-based birth cohort ...

According to the $\Lambda$CDM cosmology, present-day galaxies with stellar masses $M_\star>10^{11} {\rm M}_\odot$ should contain a sizable fraction of dark matter within their body. Models indicate that in massive early-type (ETGs) account for $\sim60\%$ dynamical mass five effective radii ($5 R_{\rm e}$). Most ETGs have been shaped through two-phase process: rapid growth compact core was follo...

stories, myths and tales can make ideas a part of popular culture. rea at religious figures have taught with parables; we use fables and fairy tales to teach our children about life; and it has been argued that even the ancient Greek myths might have been deliberate devices for organizing and transmitting information about the natural world to non-scientifically oriented people [I]. Once an ide...

This paper surveys the theoretical and empirical literature on the relationship between the spatial distribution of economic activity and transportation costs. We develop a multi-region model of economic geography that we use to understand the general equilibrium implications of transportation infrastructure improvements within and between locations for wages, population, trade and industry com...

Platelet activation and aggregation by fibrillar collagens are based on substrate primary, secondary, tertiary, and quaternary structure. Although several peptides incorporating sequences from the triple-helical domains of types I and III collagen inhibit collagen-mediated platelet aggregation, none independently promote platelet activation and aggregation. It is believed that the absence of th...

AIM To evaluate the diagnostic and prognostic value of presepsin in cirrhosis-associated bacterial infections. METHODS Two hundred and sixteen patients with cirrhosis were enrolled. At admission, the presence of bacterial infections and level of plasma presepsin, serum C-reactive protein (CRP) and procalcitonin (PCT) were evaluated. Patients were followed for three months to assess the possib...

The D1 dopamine receptor subtype is expressed in the brain, kidney and lymphocytes. D1 receptor function has been extensively studied and the receptor has been shown to modulate a wide range of physiological functions and behaviors. The expression of D1 receptor is known to change during development, disease states and chronic treatment; however, the molecular mechanisms that mediate the change...