continuous four hours eeg (electroencephalogram) recordings and its power spectrum analysis using fast fourier transform (fft) in urethane anesthetized male charles foster rats were performed in two groups: open brain injury and p-cpa (para-chlorophenylalanine) pretreated before brain injury, respectively, and compared with the eeg power spectrum of control rats. the eeg power spectrum analysis...

objective(s): preclinical studies show that iron plays a key role in mediating neuronal injury. this study was performedin order to identify the relationship between the serum level of ferritin and severity of the brain injury which occur after an intracerebral hemorrhage (ich). materials and methods:this was a cross sectional descriptive – analytic study, which was conducted on those patients ...

objective(s):this study was carried out to investigate the effects of cox-2 selective inhibitor (celecoxib) or non-selective cox inhibitor (ibuprofen) on gastrointestinal motility. materials and methods: the rats were randomly divided into five groups including: intact, sham, traumatic brain injury (tbi) group (intact rats under tbi), celecoxib group (10 mg/kg), ibuprofen group (10 mg/kg). rats...

background variables derived from electroencephalogram like cerebral state index (csi) have been used to monitor the anesthesia depth during general anesthesia. observed evidences show such variables have also been used as a detector of brain death or outcome predictor in traumatic brain-injured (tbi) patients. objectives the current study was designed to determine the correlation between glasg...

A number of animal models have been used to study hypoxic-ischemic injury, traumatic injury, global hypoxia, or permanent ischemia in both the immature and mature brain. Stroke occurs commonly in the perinatal period in humans, and transient ischemia-reperfusion is the most common form of stroke in neonates. The reperfusion phase is a critical component of injury progression, which occurs over ...

introduction: following a traumatic brain injury (tbi), the excessive release of proinflammatory cytokines is major cause of cerebral edema that can cause permanent neuronal loss. this study examined the changes in brain concentrations of proinflammatory cytokines il-1, il-6, tnf-α and tgf- after different doses of estrogen or progesterone treatment in brain-injured rats at 6 and 24 h post-in...

objective(s):estrogen (e2) has neuroprotective effects on blood-brain-barrier (bbb) after traumatic brain injury (tbi). in order to investigate the roles of estrogen receptors (ers) in these effects, er-α antagonist (mpp) and, er-β antagonist (phtpp), or non-selective estrogen receptors antagonist (ici 182780) were administered. materials and methods: ovariectomized rats were divided into 10 gr...

introduction guillain-barre syndrome (gbs) is an immune-mediated acute inflammatory disorder of the peripheral nervous system. infectious agents were usually accused of playing a role in the etiology of gbs. guillain-barre syndrome has rarely been reported following subdural and subarachnoid hemorrhage after head trauma. case presentation we report on a 63-year-old male patient presenting gbs f...

traumatic brain injury is a leading cause of death in developed countries. it is estimated that only in the united states about 100,000 people die annually in parallel among the survivors there is a significant number of people with disabilities with significant costs for the health system. it has been determined that after moderate and severe traumatic injury, brain parenchyma is affected by m...

traumatic brain injury is a common entity. however cerebral infarction in infants is a rare entity while the diagnosis of this pathology in the pediatric population is usually difficult. the mild head trauma is rarely accompanied by intracranial injury and even less, with cerebral infarction. we herein report the first case of cerebral infarction after a mild brain trauma in a 2-year-old latin-...