1. A soil bacillus has been isolated capable of developing specific adaptive enzymes which oxidize PABA apparently to carbon dioxide, water, and ammonia. A few related compounds which, however, do not give the diazo reaction are similarly attacked. 2. This bacillus is also capable of developing analogous but apparently independent adaptive enzymes specifically directed against anthranilic acid,...

One of the most pronounced differences between the commonly used sulfonamide drugs lies in their acid strength. Since the compounds, in general, seem to increase in 25 50 75 bacteriostatic efficacy in vitro as they show s IONIZED an increase in this quality, it seemed of I interest to determine what evidence, if pH any, could be gathered to support the 2 hypothesis that part, at least, of the d...

In forensic ballistics, gunshot residue (GSR) particles can be detected using screening or presumptive tests which are mainly focused on the chromophoric reaction. Most serve as an initial indication for a investigator at crime scene before instrumental analysis definitive identification. The methods known to convenient, have fast analysis, and minimal preparation. GSR well-known method of dete...

The laboratory and clinical evaluation of a potassium nitrate-saturated disk for the rapid detection of nitrate reductase production in anaerobes was investigated. The optimal disk concentration and incubation time were determined by utilizing triplicate sets of quadrant plates prepared with supplemented brucella (Difco) blood agar and swabbed with a 24-h broth (BBL; 135 C thioglycolate) suspen...

An ion-pair high performance liquid chromatographic method was developed for the simultaneous determination of p-aminosalicylic acid (PAS) and its degradation product m-aminophenol (MAP) in a newly developed multiparticular drug delivery system. Owing to the concentration differences of PAS and MAP, acetanilide and sulfanilic acid were used as internal standards, respectively. The separation wa...