نتایج جستجو برای: subcutaneous human adipocyte

تعداد نتایج: 1676266  

Journal: :Cell Metabolism 2016

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Journal: :AIDS Research and Human Retroviruses 2020

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Journal: :Diabetes 2006
Luigi Laviola Sebastio Perrini Angelo Cignarelli Annalisa Natalicchio Anna Leonardini Francesca De Stefano Marilena Cuscito Michele De Fazio Vincenzo Memeo Vincenzo Neri Mauro Cignarelli Riccardo Giorgino Francesco Giorgino

In this study, we evaluated the activation of various insulin signaling molecules in human fat in vivo and compared signaling reactions in visceral and subcutaneous fat depots. Paired abdominal omental and subcutaneous fat biopsies were obtained from nonobese subjects with normal insulin sensitivity under basal conditions and 6 and 30 min following administration of intravenous insulin. Insulin...

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2008
I J Bujalska L L Gathercole J W Tomlinson C Darimont J Ermolieff A N Fanjul P A Rejto P M Stewart

Glucocorticoid excess increases fat mass, preferentially within omental depots; yet circulating cortisol concentrations are normal in most patients with metabolic syndrome (MS). At a pre-receptor level, 11b-hydroxysteroid dehydrogenase type 1 (11b-HSD1) activates cortisol from cortisone locally within adipose tissue, and inhibition of 11b-HSD1 in liver and adipose tissue has been proposed as a ...

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Journal: :Antiviral therapy 2003
David Nolan Emma Hammond Ian James Elizabeth McKinnon Simon Mallal

OBJECTIVES It has been proposed that the contribution of nucleoside-analogue reverse transcriptase inhibitor (NRTI) therapy to subcutaneous fat wasting involves adipose tissue-specific mitochondrial DNA toxicity. We have investigated the relationships between NRTI therapy, adipocyte mitochondrial DNA content, evidence of toxicity in adipose tissue and fat wasting in Caucasian male Western Austr...

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Journal: Iranian Journal of Basic Medical Sciences 2015
Ali Jangjoo, Azam Moradi Zarmehri Daryoush Hamidi Alamdari, Jalil Tavakkol Afshari, Leila Moinzadeh, Masoumeh Arab Ameri, Meysam Ganjibakhsh, Mohammad Hadi Sadeghian, Mohammad Reza Keramati, Zahra Mohammadi,

Objective(s):Mesenchymal stem cells (MSC) can be isolated from adult tissues such as adipose tissue and other sources. Among these sources, adipose tissue (because of easy access) and placenta (due to its immunomodulatory properties, in addition to other useful properties), have attracted more attention in terms of research. The isolation and comparison of MSC from these two sources provides a ...

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Journal: :Diabetes 2008
Vanessa van Harmelen Anna Eriksson Gaby Aström Kerstin Wåhlén Erik Näslund Fredrik Karpe Keith Frayn Tommy Olsson Jonas Andersson Mikel Rydén Peter Arner

OBJECTIVE Visceral obesity increases risk of insulin resistance and type 2 diabetes. This may partly be due to a region-specific resistance to insulin's antilipolytic effect in visceral adipocytes. We investigated whether adipose tissue releases the vascular peptide endothelin-1 (ET-1) and whether ET-1 could account for regional differences in lipolysis. RESEARCH DESIGN AND METHODS One group ...

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Journal: :FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005
Kurt M Hong Marie D Burdick Roderick J Phillips David Heber Robert M Strieter

An increase in fat mass associated with obesity results from recruitment and differentiation of adipocyte progenitor cells. The precise origin of these cells is unknown, although accumulating evidence suggests that circulating stem cells can differentiate into cells of mesenchymal lineage. It is currently unclear whether a progenitor adipocyte population exists in circulation. One potential can...

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2016
Maude Giroud Didier F. Pisani Michael Karbiener Valentin Barquissau Rayane A. Ghandour Daniel Tews Pamela Fischer-Posovszky Jean-Claude Chambard Uwe Knippschild Tarja Niemi Markku Taittonen Pirjo Nuutila Martin Wabitsch Stephan Herzig Kirsi A. Virtanen Dominique Langin Marcel Scheideler Ez-Zoubir Amri

OBJECTIVE In rodents and humans, besides brown adipose tissue (BAT), islands of thermogenic adipocytes, termed "brite" (brown-in-white) or beige adipocytes, emerge within white adipose tissue (WAT) after cold exposure or β3-adrenoceptor stimulation, which may protect from obesity and associated diseases. microRNAs are novel modulators of adipose tissue development and function. The purpose of t...

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Journal: :Diabetes 2006
Tamara Tchkonia Nino Giorgadze Tamar Pirtskhalava Thomas Thomou Matthew DePonte Ada Koo R Armour Forse Dharmaraj Chinnappan Carmen Martin-Ruiz Thomas von Zglinicki James L Kirkland

Fat depots vary in size, function, and potential contribution to disease. Since fat tissue turns over throughout life, preadipocyte characteristics could contribute to this regional variation. To address whether preadipocytes from different depots are distinct, we produced preadipocyte strains from single abdominal subcutaneous, mesenteric, and omental human preadipocytes by stably expressing h...

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نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید

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