background: seborrheic keratoses (sk) are common, benign and often multiple skin tumors with disputed etiology. a follicular origin, late onset nevoid disturbance or local arrest in maturation of keratinocytes have been proposed. human papilloma virus (hpv) has been detected in a small number of cases, particularly those from the genital region. objectives: the aim of our study was to evaluate ...

The object of this investigation was to distinguish between two potential mechanisms of activation of human plasminogen (HPg) to plasmin (HPm) by catalytic levels of the activator complex, streptokinase.plasmin (SK* .HPm). One mechanism, which is widely supported, postulates an enzymatic role for SK*. HPm in the conversion of molar excesses of plasminogen to plasmin. A more recently described k...

AIMS To determine antistreptokinase antibody (anti-SK) titres in patients with the acute coronary syndrome from communities with endemic group A streptococcal infection because of the implications for streptokinase (SK) thrombolysis. METHODS Anti-SK titres were determined using a standard method in 47 consecutive SK naive patients, presenting to the Mt Isa Hospital emergency department, Austr...

introduction: oxidative stress and neuroinflammation are involved in neurodegeneration procedure in parkinson’s disease. recently, neuroprotective potential of boswellia resin has been demonstrated. therefore, this study examined whether administration of boswellia resin would attenuate mpp+- induced neuronal death in sk-n-sh- cell line, a human dopaminergic neurons- in vitro. methods: boswelli...

INTRODUCTION Loss of inhibitory output from Purkinje cells leads to hyperexcitability of the Deep Cerebellar Nuclei (DCN), which results in cerebellar ataxia. Also, inhibition of small-conductance calcium-activated potassium (SK) channel increases firing rate of DCN, which could cause cerebellar ataxia. Therefore, SK channel activators can be effective in reducing the symptoms of this disease, ...

BACKGROUND Streptokinase is the most widely used thrombolytic agent and can now be made using recombinant DNA technology. The present trial was initiated to assess an indigenous recombinant streptokinase (Shankinase, r-SK). AIM To compare the efficacy and safety of indigenous recombinant streptokinase (Shankinase, r-SK) and natural streptokinase (Streptase, n-SK). SETTINGS AND DESIGN Double...

psa is a 33-kda serine protease that is produced predominantly by prostate epithelium. however, it has been shown that about 30-40% of female breast tumors produce psa and its production is associated with the presence of estrogen and progesterone receptors. we have now developed a new tissue culture system to study psa production in breast cancer and its association with prognostic factors suc...

conclusions: thus, identifying the hf patients before the flight and providing them proper education about the events that may occur during flight is necessary. results: hf patients are more prone to experience respiratory distress, anxiety, stress, cardiac decompensation, and venous thromboembolism (vte) during air travel. although stable hf patients can tolerate air travel, but those with acu...

By using the notions of exact truth (‘true and not false’) and exact falsity (‘false and not true’), one can give 16 distinct definitions of classical consequence. This paper studies the class of relations that results from these definitions in settings that are paracomplete, paraconsistent or both and that are governed by the (extended) Strong Kleene schema. Besides familiar logics such as Str...

Seborrheic keratosis (SK) is the most common benign cutaneous neoplasm. A subset shows increased p16 expression. Since SK shares several features with verruca vulgaris, e.g., increased p16 expression, human papillomaviruses (HPV) have been suggested as possible causal agents. However, a relevant association could not be established between HPV and SK. In the present study we aimed to investigat...