For ages, medicinal plants play a significant role in the effective, affordable, and safe healthcare system. Medicinal continue to an important Nigeria's system, which serves more than 70% of country's population. pharmaceutical exploration conservation, it is document use specific region across time. The study's goal was find out were used treat typhoid illness Kaduna state. in-depth interview...

At 50% maturity, regenerating Senna species were characterized for morphological traits, seed reproduction, and evaluated for regeneration. Quality plants regenerated from all accessions produced 1018 to more than 21,215 total seeds. Principal component analysis revealed which traits contributed the greatest to variability among coffee senna accessions. Senna species have potential to produce p...

BACKGROUND Surreptitious ingestion of laxatives can lead to serious factitious diseases that are difficult to diagnose. Most cases involve ingestion of bisacodyl or senna. Thin layer chromatography (TLC) of urine or stool is the only commercially available test for these laxatives. Such testing is considered highly reliable, but its accuracy in clinical practice is unknown. Our aim was to evalu...

Due to their natural origin, apparent low oral toxicity, effectiveness, and accessibility without a medical prescription, the anthranoid laxatives are a popular remedy for constipation and are frequently used abusively. Therefore, it is important to characterize its harmful and/or toxic effects. The sennosides, main active metabolites of senna, exhibit a very low toxicity in rats, and its genot...

Objective: The aim of this study was to develop and validate an image analysis method for quantitative analysis of barakol content in Senna siamea leaf extract. Methods: TLC-densitometric and TLC-image analysis methods were developed, validated, and used for quantitative analysis of Senna siamea leaf extract. The results obtained by these two different quantification methods were compared by pa...

The direct action of intraluminal senna and related compounds on the human colon and rectum has been investigated. Motility was recorded by balloon kymography with recording units inserted into well established transverse colostomies or into the rectum. The motility of the colon was not changed by intraluminal senna glycosides but the introduction of senna previously incubated with faeces or Es...