Dementia is one of the most disabling and burdensome health conditions worldwide. In this study, we identified new potential risk factors for dementia from nationwide longitudinal population-based data by using Bayesian statistics.We first tested the consistency of the results obtained using Bayesian statistics with those obtained using classical frequentist probability for 4 recognized risk fa...

IT is well known that the human lens is rich in glutathione and that this substance disappears totally from the lens in senile cataract. Glutathione is remarkable in being the most labile sulphur-containing substance in the body. It is, as we know, closely associated with tissue respiration, which assumes special importance in a non-vascular tissue such as the lens. The relation of glutathione ...

PURPOSE To investigate the aqueous humor, lens, and serum concentrations of zinc, iron, and copper in patients with pseudoexfoliative cataract and compare with patients who have senile cataract without pseudoexfoliation. METHODS Twenty-five patients with pseudoexfoliative cataract and 25 patients with senile cataract as control group were enrolled in the study. Samples from aqueous humor, ser...

Comparison of free amino acids in freshly excised rabbit lenses and in lenses taken from the contralateral eyes after storage for 24 to 48 hours reveals essentially no postmortem changes. This suggests that human eyebank lenses may be considered as normal with respect to the free amino acid pool. Analysis of senile cataractous lenses, compared to eyebank lenses, reveals a wide range of amino ac...

Comparison of free amino acids in freshly excised rabbit lenses and in lenses taken from the contralateral eyes after storage for 24 to 48 hours reveals essentially no postmortem changes. This suggests that human eyebank lenses may be considered as normal with respect to the free amino acid pool. Analysis of senile cataractous lenses, compared to eyebank lenses, reveals a wide range of amino ac...

We have studied the clarifying activity of a purified peptide fraction of gametic origin in senile cataract of the dog. The active substance, administered intramuscularly, had significant and durable clarifying effects on the cortical area of the lens.