The telencephalon is one of the most complex parts of the brain, and its patterning is still poorly understood. In this issue of Neuron, describe a novel Wnt antagonist Tlc, a member of the secreted Frizzled-related protein (sFrp) family. Secreted from the anterior boundary of the zebrafish neural plate, Tlc appears to protect the telencephalon from obliteration by a more caudal neural Wnt signal.

Breast carcinoma is the most frequent form of malignancy in women globally. Exploration breast cancer genome tiled way for validation novel biomarkers and to explore various mechanisms involved progression carcinogenesis. The purpose research find an identification potential gene linked (BC) prognosis. Three datasets (GSE71053, GSE61724, GSE36295) were downloaded from Gene Expression Omnibus (G...