Background: Sclareol is a phytochemical used in people's diet in Southeast Asia. Objective: To investigate the immunotherapeutic effectiveness of Sclareol against breast cancer by direct intraperitoneal injection. Methods: Sclareol was isolated and purified from Salvia sclarea. Effect of Sclareol on cell growth inhibition was evaluated by MTT assay. Intraperitoneally injected Sclareol effects o...

BACKGROUND Although Salvia sclarea (clary sage) is widely used in aromatherapy and has antioxidant and antimicrobial properties, its mechanisms of action remain poorly understood. We therefore assessed whether clary sage is effective in treating endothelial dysfunction induced by chronic immobilization stress in rats. METHODS Rats were intraperitoneally injected with almond oil, clary sage oi...

The genus Salvia L. has more than 900 species distributed throughout the globe. 21 are growing in Ukraine. All of this have essential oils. officinalis and sclarea been used culture widely medical practice. chemical composition other sage possibility their use pharmaceutical practice almost not studied. Taking into account results chemotaxonomic studies flora Ukraine, prevalence prospects for i...

objective(s) due to increasing emergence of drug-resistance in helicobacter pylori isolates, traditional plants are potentially valuable sources of novel anti-h. pylori agents. in this research, anti-h. pylori activity of the organic extracts of twenty native iranian plants was determined against ten clinical isolates of h. pylori. materials and methods disc diffusion was used to determine the ...

In previous studies of the incorporation of sodium acetateZ-Cl4 (1, 2) and sodium mevalonate-2-C14 (2) into &sitosterol and the acidic triterpenes of Salvia oficinalis, Cl4 from both precursors was found in sterol and triterpenes. The presence of sclareol (Fig. l), /3-sitosterol, oleanolic acid, and ursolic acid II (3, 4) in the plant Xalvia sclarea has afforded an opportunity to duplicate thes...