The molecular chaperone Hsp104 is a crucial factor in the acquisition of thermotolerance in yeast. Under stress conditions, the disaggregase activity of Hsp104 facilitates the reactivation of misfolded proteins. Hsp104 is also involved in the propagation of fungal prions. For instance, the well-characterized [PSI(+)] prion of Saccharomyces cerevisiae does not propagate in Deltahsp104 cells or i...

The replication terminator protein Fob1 of Saccharomyces cerevisiae is multifunctional, and it not only promotes polar replication fork arrest at the tandem Ter sites located in the intergenic spacer region of rDNA but also loads the NAD-dependent histone deacetylase Sir2 at Ter sites via a protein complex called RENT (regulator of nucleolar silencing and telophase exit). Sir2 is a component of...

Saccharomyces bayanus var. uvarum investigated here is the species closest to Saccharomyces cerevisiae. Random sequence tags (RSTs) allowed us to identify homologues to 2789 open reading frames (ORFs) in S. cerevisiae, ORFs duplicated in S. uvarum but not in S. cerevisiae, centromeres, tRNAs, homologues of Ty1/2 and Ty4 retrotransposons, and a complete rDNA repeat. Only 13 RSTs seem to be homol...

Nghiên cứu được thực hiện với mục đích phân lập và tuyển chọn nấm men Saccharomyces cerevisiae (S. cerevisiae) định hướng sản xuất probiotics dùng trong chăn nuôi. Kết quả nghiên đã 32 chủng từ 52 mẫu chất chứa ruột gà khoẻ mạnh. Dựa vào đặc điểm hình thái, sinh hóa danh bằng phương pháp khuếch đại vùng gen ITS xác 3 (Y35, Y63, Y100) thuộc loài S. cerevisiae. Ba này sàng lọc thêm các tính khác ...

biosorption of two anionic dyes, eosin y and eosin b, from aqueous solution using saccharomyces cerevisiae was investigated in a batch mode. the influence process parameters such as contact time, initial dye concentration, sorbent dosage, ph and temperature of aqueous solution were studied. the maximum adsorption capacities were found to be at 200 and 100 mg g-1 for eosin y and 1 eosin b, respe...

there is a great call for using microbial bio-decaffeination approach to remove caffeinefrom caffeinated products and industrial wastes. we aimed in this study to screen strainsof yeasts which exhibit high caffeine tolerance and to investigate the bio-degradation ofcaffeine under growth conditions. sixteen yeast strains were isolated from the cultivatedtea soils collected from sites of northern...

background and purpose: microorganism-based synthesis of nanostructures has recently been noted as a green method for the sustainable development of nanotechnology. nowadays, there have been numerous studies on the emerging resistant pathogenic bacteria and fungal isolates, the probable inability of bacteria and fungi to develop resistance against silver nanoparticles’ (snps) antibacterial, ant...

Yeast Zuotin and Ssz are members of the conserved Hsp40 and Hsp70 chaperone families, respectively, but compared with canonical homologs, they atypically form a stable heterodimer termed ribosome-associated complex (RAC). RAC acts as co-chaperone for another Hsp70 to assist de novo protein folding. In this study, we identified the molecular basis for the unusual Hsp70/Hsp40 pairing using amide ...

A MHC6 complex of a platinum group metal with a capped octahedral arrangement of donor atoms around the metal center has been characterized. This osmium compound OsH{κ(2) -C,C-(PhBIm-C6 H4 )}3 , which reacts with HBF4 to afford the 14 e(-) species [Os{κ(2) -C,C-(PhBIm-C6 H4 )}(Ph2 BIm)2 ]BF4 stabilized by two agostic interactions, has been obtained by reaction of OsH6 (PiPr3 )2 with N,N'-diphen...

Internet and IT have re-shaped the strategy logic of contemporary organizations. The new logic emphasizes business opportunity leveraging through constantly evolving entrepreneurial actions. The required business capabilities underlying such strategic logic, including organizational agility and IT competence, have also to be built and co-evolved. Based on Sambamurthy et al. [1] conceptual frame...