In an endeavor directed towards the construction of the oxabicyclic[3.2.1]octane segment present in the bioactive natural products of cortistatins and icetexanes genre, the title compound, C(13)H(19)BrO(3), was synthesized from (4aR,9aS)-1,3,4,4a,5,6,9,9a-octa-hydro-spiro-[benzo[7]annulene-2,2'-[1,3]dioxolane]-4a-ol via a transannular bromo-etherification protocol. The six-membered ring adopts ...

Interleukin (IL)-12 is a 70-kDa cytokine comprised of two disulfide-linked proteins (p35 and p40) and is essential for the initiation of effective immune response. Granulocyte-colony stimulating factor (G-CSF) affects the balance in the production of anti-inflammatory cytokines. We investigated the serum IL-12 p40 and IL-12 Mix (p40 and p70) production in 28 patients with B-cell lineage non-Hod...

We show that #9(S 2 S 3) admits an 8-dimensional complex family of inequivalent non-regular Sasakian-Einstein structures. These are the rst known Einstein metrics on this 5-manifold. In particular, the bound b 2 (M)8 which holds for any regular Sasakian-Einstein M does not apply to the non-regular case. We also discuss the failure of the Hitchin-Thorpe inequality in the case of 4-orbifolds and ...

The Marketing Mix comprises of four decisions which should be considered before launching a product. Firms should plan targeted approach on these four different components and they are Product, Price, and Place & Promotion. All the four variables help the firm in formulating strategic decisions necessary for competitive advantage. The main objective of this article is to describe the importance...

The language MIX consists of all strings over the three-letter alphabet {a, b, c} that contain an equal number of occurrences of each letter. We prove Joshi’s (1985) conjecture that MIX is not a tree-adjoining language.

The purpose of the this study was to evaluate the cytotoxicity of dental resin monomers in the presence of a rat liver S9 mix containing cytochrome P 450 enzymes. JTC-12 cells derived from a monkey kidney were seeded on a 96-well multi-well-plate at 9 x 10(3) cells per well. After cultivation, the S9 mix was added to the wells as an S9 mix group (+S9), and PBS- was added to the other wells as a...

Golle, Zhong, Boneh, Jakobsson, and Juels [9] recently presented an efficient mix-net, which they claim to be both robust and secure. We present five practical attacks for their mix-net, and break both its privacy and robustness. The first attack breaks the privacy of any given sender without corrupting any mix-server. The second attack requires that the first mix-server is corrupted. Both atta...

Five isomeric epoxyhydroxyene and epoxyoxoene fatty esters derived from hemolytic decomposition of linoleic acid hydroperoxide were tested for mutagenicity by the "Ames' top-agar incorporation method using S-9 mix derived from livers of male rats pretreated with Aroclor 1254. The epoxide fatty esters tested--methyl trans-12,13-epoxy-erythro-11-hydroxy-cis(trans)-9-octadecenoate and methyl trans...

Abstract TR material is the abbreviation of glutinous rice and tung oil, which a traditional organic reinforcement since ancient China. Taking Qiantang River silt reinforced with as research object, 9 samples different mass mix proportions were placed in standard curing environment (20 °C, humidity 60%) for 7 days, 14 30 90 days 180 respectively. Shear test, permeability test dry-wet cycle carr...