Although rotavirus vaccines are available, rotaviruses remain the major cause of childhood diarrheal disease worldwide. The Rotarix (GlaxoSmithKline Biologicals Rixensart, Belgium) and RotaTeq (Merck and Co., Inc. Whitehouse Station, New Jersey, USA) vaccines are effective for reducing the morbidity and mortality of rotavirus infection. This article aims to assess the epidemiology of rotaviral ...

Nausea and vomiting commonly occur in children suffering from rotaviral diarrhoea. Gastric emptying was studied in 10 children (age six to 12 months) suffering from acute diarrhoea caused by rotavirus using a dye dilution double sampling technique. The test meal was 5% dextrose in water and this test was repeated 12 weeks after recovery. The median (range) of the percentages of the liquid meal ...

Infectious diseases of both humans and farm animals are re-emerging as significant problems, because our arsenal of effective anti-infective tools is not expanding proportionally. Thus, there is an urgent need for new approaches to the treatment of infectious disease, especially in cases of drug-resistant microbes, microbes for which therapy is not available, or in cases of host immune impairme...

BACKGROUND Rotaviral diarrhoea kills about half a million children annually in developing countries and accounts for one third of diarrhea related hospitalizations. Drugs and vaccines against the rotavirus are handicapped, as in all viral diseases, by the rapid mutational changes that take place in the DNA and protein sequences rendering most of these ineffective. As of now only two vaccines ar...