PURPOSE To assess whether brimonidine 0.15% alters retinal vascular autoregulation and short-term visual function in normal tension glaucoma patients who demonstrate retinal vascular dysregulation. DESIGN Nonrandomized clinical trial. METHODS In this prospective study, 46 normal tension glaucoma patients not previously treated with brimonidine underwent retinal vascular autoregulation testi...

BACKGROUND Acute retinal necrosis is a rare but devastating ocular condition. We report two cases of acute retinal necrosis in immunocompetent patients, complicated by cystoid macular oedema and treated with intravitreal dexamethasone (OZURDEX®) implant. RESULTS Two patients diagnosed with acute retinal necrosis were treated with intravenous acyclovir. Both of them developed cystoid macular o...

Retinal vascular anomalies are a heterogeneous group consisting of congenital and acquired lesions. The visual prognosis varies in wide range from asymptomatic to advanced vision loss according the location lesion. Diagnosis is made by fundus examination, fluorescein angiography, optical coherence tomography. It may be associated with systemic diseases require detailed examination. This review ...

We report a rare case of isolated unilateral acute retinal necrosis syndrome without any history of associated herpes zoster or other conditions attributed to HIV infection as the initial manifestation of HIV infection. A 30-year-old man presented with a history of sudden diminished vision in the right eye with no apparent predisposing factors. Examination revealed right eye acute retinal necro...

retinal vein occlusion (rvo) is a common retinal vascular occlusive disorder and is associated with a variety of systemic risk factors. the aim of this study was to investigate whether the underlying diseases were evaluated and managed appropriately by ophthalmologists. we performed a study of 1344 patients with retinal vein occlusion (rvo). patients were evaluated with a questionnaire includin...

PURPOSE Stem cell factor (SCF) has been recently acknowledged as a novel endothelial permeability factor. However, the mechanisms by which SCF-induced activation of the SCF cognate receptor, cKit, enhances endothelial permeability have not been fully elucidated. This study aimed to investigate the role of Src in SCF-induced breakdown of the blood-retinal barrier (BRB). METHODS In vitro endoth...