methicillin-resistant staphylococcus aureus (mrsa) is a major cause of nosocomial infections all around the world. mrsas are usually present in health care centers and hospitals. nowadays methicillin-resistant mrsas in two groups of healthcare associated mrsa (ha_mrsa) and community associated mrsa (ca_mrsa)were studied. predisposing factors for ha_mrsa infections included hemodialysis, surgery...

staphylococcus aureus is an opportunistic pathogen and remains a common cause of burn wound infections. different studies have shown that entrapment of plant-derived compounds into liposomes could increase their anti-staphylococcus aureus activity. silymarin is the bioactive extract from the known plant silybum marianum l. the objective of this study was to evaluate efficacy of silymarin in fre...

conclusions the results illustrated the diversity of antibacterial resistance and virulence gene profiles among different sccmec types of s. aureus. the increased prevalence of methicillin-resistant s. aureus isolates containing different toxin and antibiotic resistance genes is a serious threat for the hospitalized patients in the intensive care units. methods in this cross-sectional study tha...

nasal mupirocin is found to eradicate effectively methicillin-resistant staphylococcus aureus (mrsa) from colonized patients, but there are concerns about resistant strains. the aim of this study was to detect the mupirocin resistance and nasal carriage of methicillin resistant s. aureus among healthcare workers (hcws) at the university hospitals of tehran.totally 270 nasal swabs were collected...

conclusions similarly to other geographical regions of iran, the sccmec type iii mrsa strain was the most frequently isolated strain from patients in gorgan. staphylococcal cassette chromosome mec type iii showed fewer virulence factors compared to other sccmec types. results the most common sccmec type was type iii, with a frequency rate of 76%, followed by types iv, i, and v, with frequency r...

background methicillin-resistant staphylococcus aureus (mrsa) continues to be a major cause of nosocomial infections. methicillin resistance in s. aureus is caused by the acquisition of the meca gene, located on a mobile genetic element called the staphylococcal cassette chromosome (scc). objectives the aim of this study was to evaluate the presence of the predominant sccmec type present among ...

background methicillin -resistant staphylococcus aureus (mrsa) is associated with serious infections. having the ability of biofilm-formation decrease their susceptibility to antibiotics. objectives the aim of this study was to determine the prevalence of biofilm formation among mrsa isolated from nasal carriers in the beheshti teaching hospital in kashan, iran. materials and methods a cross-se...

The article presents a synthetic molecular characterization of the methicillin-resistant Staphylococcus aureus and describes the most important community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) clones that circulate nowadays in the world: the main molecular and epidemiological characteristics, as well as notions related to the clinic of infections produced by these clones...

In the present study, the effectiveness of a rapid and colorimetric nitrate reductase analysis (NRA) method and resazurin microplate assay (REMA) for rapid determination of methicillin resistance among Staphylococcus aureus was investigated. A total of 275 clinical isolates of S. aureus were included in the present study. Among these isolates, 151 had the mecA gene and were resistant to methici...

We evaluated the activity of ceftobiprole against 100 community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) and 100 hospital-associated MRSA (HA-MRSA) isolates. Eight isolates were evaluated by time-kill studies for kill rate and potential for synergy with tobramycin. Ceftobiprole MIC(50) and MIC(90) values were 1 and 2 microg/ml, respectively, against CA-MRSA and HA-MRSA. ...