• Nephreetomized dogs given sodium parenterally and protein by diet develop acute hypertensive cardiovascular disease.' Protection, against acute renoprival hypertension of this type has been demonstrated for (a) intact renal tissue as exemplified by ureterocaval anastomosis, (b) autoexplanation of whole kidney or renal medulla, and (c) a crude extract of renal medulla. Both medullorenal extrac...

Background & Aims: Liver ischemia-reperfusion (IR) is one of the common consequences of liver surgery, especially during liver transplantation which results in organ dysfunction. Acute hepatic injury causes systematic inflammatory responses which may finally lead to functional disturbances in remote organs such as heart, lungs and kidneys. In this study, the effects of a potent inhibitor of inf...