OBJECTIVE Because many patients with diabetic macular edema (DME) do not respond to focal/grid laser photocoagulation, the only currently approved treatment, alternatives are needed. Based on encouraging preliminary findings, we aimed to assess efficacy and safety of the anti-tumor necrosis factor (TNF) monoclonal antibody infliximab in this condition. RESEARCH DESIGN AND METHODS This was a s...

BACKGROUND The causative role of diffuse macular edema in various etiologies is often undetermined. OBJECTIVES To describe an association between extrafoveal vitreous traction and non-diabetic diffuse macular edema secondary to various ocular entities. METHODS In a retrospective study of eyes with non-diabetic diffuse macular edema, charts and optical coherence tomography scans demonstratin...

PURPOSE To evaluate the effectiveness of intravitreal triamcinolone injection on the course of diabetic macular edema. METHODS Forty-eight eyes of 48 diabetic patients were treated with 8 mg of intravitreal triamcinolone injection as the primary therapy for diabetic macular edema. The main outcome measures included best-corrected visual acuity, fundus fluorescein angiography, macular edema ma...

Diabetic macular edema represents one of the most important causes of visual morbidity in diabetes mellitus. The National Diabetes Information Clearinghouse estimates the prevalence of diabetes mellitus types 1 and 2 at 11.3% of the population above the age of 20, with an annual incidence of 1.9 million cases in the United States alone. In this population, the prevalence of diabetic macular ede...

Macular edema is the leading cause of vision loss in increasingly frequent occurrence diabetes mellitus, a true epidemic developed countries. Diabetic macular closely related to lifestyle, obesity, smoking or high blood pressure. oedema people with countries, and its prevalence directly duration diabetes. Its incidence varies from publication publication, ranging between 7.5% 15.2%, more common...

Diabetic retinopathy is fast emerging as a leading cause of newly diagnosed legal blindness amongst the working population. Macular edema, as it is commoner, accounts for more vision impairment than neovascular proliferation in diabetic patients. Laser photocoagulation, which is the standard treatment of macular edema, is associated with significant complications and an improvement in visual ac...

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OBJECTIVE We examined the endothelial nitric oxide (eNOS) gene polymorphisms to assess its possible association with diabetic retinopathy and macular edema. RESEARCH DESIGN AND METHODS A total of 226 patients with type 2 diabetes and 186 healthy subjects were studied. Type 2 diabetic patients consisted of 110 patients without retinopathy, 46 patients with nonproliferative diabetic retinopathy...

1676. May 4, 2009. 17. Jaffe GJ, Martin D, Callanan D, et al. Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis: thirtyfour-week results of a multicenter randomized clinical study. Ophthalmology. 2006 Jun;113(6):1020-7. 18. Macugen Diabetic Retinopathy Study Group. A phase II randomized double-masked trial of pegaptanib, an anti-vascular endothelial growth factor apt...