OBJECTIVE To report a case of reversible nonthrombocytopenic palpable purpura associated with metoclopramide. CASE SUMMARY A 72-year-old white man was admitted for worsening palpable purpura over a two-day period. Two days prior to admission, metoclopramide 10 mg orally three times per day was started for a gastrointestinal condition. Upon admission, all drugs were continued except metoclopra...

Immune thrombocytopenic purpura and venous thromboembolism are rare but known complications of ulcerative colitis. Although several case studies have examined the treatment options available for ulcerative colitis patients presenting with immune thrombocytopenic purpura, there have been no reported cases that describe the optimal treatment for patients with ulcerative colitis and immune thrombo...

Background: Purpura is a common adverse effect of dermatological procedures and can compromise the patients’appearance especially when they occur on the face. Topical vitamin K oxide has been known to be effective in treatment of purpura from vascular laser and minor surgical procedures. However its effectiveness on purpuric skin with minimal ablation produced by Q-switched Nd-YAG laser has not...

Henoch-Schonlein Purpura (HSP) is an acute immunoglobulin A (IgA)–mediated disorder characterized by generalized vasculitis. HSP commonly occurs in children. The annual worldwide incidence 13-20 per 100,000 children under 17 years of age.1–3 It non-thrombocytopenic palpable purpura mostly located on the dependent parts like lower extremities and buttocks, arthralgia/arthritis, bowel angina, hem...

objective: thrombotic thrombocytopenic purpura (ttp) is the most malignant variant of microangiopathy that usually presents by typical symptoms including thrombocytopenia, hemolytic anemia, neurological abnormalities, fever and renal impairment. report of the case: we report a 12-year-old male presented by cytopenia, fever, purpura on his extremities, seizure and lethargy. peripheral blood smea...

1. Sharis PJ, Cannon CP, Loscalzo J. The antiplatelet effects of ticlopidine and clopidogrel. Ann Intern Med 1998; 129:394-405. 2. Mc Tavish D, Faulds D, Goa KL. Ticlopidine: an updated review of its pharmacology and therapeutic use in platelet-dependent disorders. Drugs 1990; 40:238-59. 3. Page Y, Tardy B, Zeni F, Comtet C, Terrana R, Bertrand JC. Thrombotic thrombocytopenic purpura. 1991; 337...

Association of immune thrombocytopenic purpura and tuberculosis is a rare condition. In 5 patients presenting with this association, anti-tuberculous therapy was effective on both tuberculosis and thrombocytopenia suggesting a causal relationship between tuberculosis and immune thrombocytopenic purpura

Cutaneous vasculitis is frequently located on the lower limbs. We describe a patient who developed palpable purpura affecting the penis as the presenting sign of more widespread lesions of Henoch-Schönlein purpura.

Leeches are prevalent in the Australian Rainforest. We report two cases of leech bites resulting in pruritis and palpable purpura. The dermatologic sequelae of leech bites, differential diagnosis of pruritic palpable purpura, leech bite treatment, prevention, and complications are reviewed.

A case of relapsing and refractory thrombotic thrombocytopenic purpura received mycophenolate mofetil (MMF) to attempt to maintain remission. The possible use of MMF in thrombotic thrombocytopenic purpura is discussed.