NO produced by NO synthase type 3 (NOS3) in medullary thick ascending limbs (mTHALs) inhibits Cl(-) reabsorption. Acutely, angiotensin II stimulates thick ascending limb NO production. In endothelial cells, NO inhibits NOS3 expression. Therefore, we hypothesized that angiotensin II decreases NOS3 expression via NO in mTHALs. After 24 hours, 10 and 100 nmol/L of angiotensin II decreased NOS3 exp...

The nitric oxide (NO)-cGMP signaling pathway is implicated in an increasing number of experimental models of plasticity. Here, in a behavioral analysis using one-trial appetitive associative conditioning, we show that there is an obligatory requirement for this pathway in the formation of long-term memory (LTM). Moreover, we demonstrate that this requirement lasts for a critical period of appro...

Abstract The breaking of dormancy mediated by reactive nitrogen species (RNS) is related to the accumulation oxygen (ROS) in germinating embryos but underlying mechanism unclear. objectives this study were: (1) explore relationship between RNS-mediated release and ROS Sorbus pohuashanensis ; and, (2) investigate relationships among germination time, metabolism, endogenous hormone synthesis. We ...

Despite recent efforts to elucidate the regulation of stomatal movement, many components within the branched pathways of guard cell abscisic acid (ABA) signaling remain to be identified. Here, we show results supporting the involvement of nitric oxide (NO) as a new component of this signaling pathway. NO is a short life bioactive molecule first described as a toxic compound, but now recognized ...

Low-temperature storage is convenient for postharvest preservation of peach fruit, but fruit sensitive to cold damage, which lowers its quality. Nitric oxide (NO) has the potential improve bitter resistance fruit. In this work, was treated with 15 ?mol L?1 NO and 5 c-PTIO [2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxo-3-oxide], study changes in mitochondrial fatty acids expression C-...

The photoreceptors of Drosophila express a nitric oxide-sensitive guanylate cyclase during the first half of metamorphosis, when postsynaptic elements in the optic lobe are being selected. Throughout this period, the optic lobes show NADPH-diaphorase activity and stain with an antibody to nitric oxide synthase (NOS). The NOS inhibitor L-NAME, the NO scavenger PTIO, the sGC inhibitor ODQ, and me...