نتایج جستجو برای: protein tyrosine phosphatase 1b

تعداد نتایج: 1300053  

Journal: :Organic & biomolecular chemistry 2015
Viacheslav V Trush Sergiy G Kharchenko Vsevolod Yu Tanchuk Vitaly I Kalchenko Andriy I Vovk

Monoester derivatives of thiacalix[4]arene tetrakis(methylphosphonic) acid were found to be capable of inhibiting protein tyrosine phosphatase 1B. In addition, these compounds can strongly bind to human serum albumin.

Journal: :iranian journal of allergy, asthma and immunology 0
somayeh ahmadloo department of medical genetics, school of medicine, tehran university of medical sciences, tehran, iran. mohsen taghizadeh department of medical genetics, school of medicine, tehran university of medical sciences, tehran, iran. mohsen akhiani department of rheumatology, alborz hospital, karaj, iran. ahmad salimzadeh rheumatology research center, sina hospital, tehran university of medical sciences, tehran, iran. mohammad keramatipour department of medical genetics, school of medicine, tehran university of medical sciences, tehran, iran.

the rs2476601 (r620w, c1858t) polymorphism in ptpn22 gene has been repeatedly reported to be associated with rheumatoid arthritis (ra). the rs 2476601 is widely suggested for predictive testing and risk assessment for ra. the aim of this study was to test the possible association of this snp with ra in iranian population.a total of 872 samples (405 confirmed ra patients and 467 healthy controls...

Journal: :The Journal of biological chemistry 1999
S M Schoenwaelder K Burridge

Activation of the thiol protease calpain results in proteolysis of focal adhesion-associated proteins and severing of cytoskeletal-integrin links. We employed a commonly used inhibitor of calpain, calpeptin, to examine a role for this protease in the reorganization of the cytoskeleton under a variety of conditions. Calpeptin induced stress fiber formation in both forskolin-treated REF-52 fibrob...

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