This study was aimed at determining the effect of duloxetine (a serotonin-norepinephrine reuptake inhibitor) on pudendal inhibition of bladder overactivity. Cystometrograms were performed on 15 cats under α-chloralose anesthesia by infusing saline and then 0.25% acetic acid (AA) to induce bladder overactivity. To inhibit bladder overactivity, pudendal nerve stimulation (PNS) at 5 Hz was applied...

Introduction The incidence of nonmelanoma cutaneous head and neck malignancies is increasing worldwide. In a small percentage of cases, associated perineural spread (PNS) of cranial nerves occurs, resulting in poor prognosis, with a recorded 5-year survival rate of 50% to 64.3%. Patients with clinical PNS from cutaneous head and neck malignancies are treated with surgical resection and postoper...

Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh budaya organisasi terhadap kinerja PNS, motivasi kerja kepuasan organisasi, kerja, PNS melalui di Kantor Kecamatan Kota Waingapu. Metode penelitian yang digunakan adalah kuantitatif dengan menggunakan kueisoner sebagai bahan pengumpulan data dianalisis bantuan software SPSS versi 25. Populasi dalam berjumlah 14 orang, sehingga ...

OBJECTIVE To examine the extent to which smokers express negative statements about quitting and the extent to which these statements influence general practitioners' (GPs') and practice nurses' (PNs') (dis)continuation of guideline-recommended smoking cessation care. METHODS Fifty-two video-consultations were observed (GP-consultations: 2007-2008; PN-consultations: 2010-2011). Dialogues were ...

Morphology and function of the nervous system is maintained via well-coordinated processes both in central and peripheral nervous tissues, which govern the homeostasis of organs/tissues. Impairments of the nervous system induce neuronal disorders such as peripheral neuropathy or cardiac arrhythmia. Although further investigation is warranted to reveal the molecular mechanisms of progression in ...

Highly specialized glial cells wrap axons with a multilayered myelin membrane in vertebrates. Myelin serves essential roles in the functioning of the nervous system. Axonal degeneration is the major cause of permanent neurological disability in primary myelin diseases. Many glycoproteins have been identified in myelin, and a lack of one myelin glycoprotein results in abnormal myelin structures ...

Petri nets (PNs) are a qualitative approach to modeling the gene regulatory networks (GRNs) capable of characterising the dynamical properties of complex systems while also describing their structure with PN graphs. In this paper we show how to construct basic building blocks for GRNs using PNs. We present solutions to some of the known weaknesses of using conventional PNs for descrbing GRNs by...

Patients commonly seek care from their family physicians for symptoms that are suggestive of peripheral nervous system (PNS) dysfunction. At some point in active practice, virtually all family physicians will be required to conduct at least an initial evaluation of a patient with PNS. The authors outline and describe common themes found in the symptoms and diagnoses of PNS dysfunctions. These t...

In the Drosophila antennal lobe, excitation can spread between glomerular processing channels. In this study, we investigated the mechanism of lateral excitation. Dual recordings from excitatory local neurons (eLNs) and projection neurons (PNs) showed that eLN-to-PN synapses transmit both hyperpolarization and depolarization, are not diminished by blocking chemical neurotransmission, and are ab...

Structured peer-to-peer (p2p) overlay networks provide a useful substrate for building distributed applications. They assign object keys to overlay nodes and provide a primitive to route a message to the node responsible for a key. Proximity neighbor selection (PNS) can be used to achieve both low delay routes and low bandwidth usage but it introduces high overhead. This paper presents a detail...