Novel palladium, rhodium, iron, ruthenium and nickel half-sandwich picolinamide complexes have been prepared characterised in detail using high-resolution electrospray ionisation mass spectrometry (HR-ESI-MS), multi-dimensional nuclear magnetic resonance spectroscopy, elemental analysis (EA), Fourier transform-infrared spectroscopy (FT-IR), single crystal X-ray diffraction (SCXRD). All the syst...

Pancreatic islet cell tumors were induced in 38 of 44 male Wistar rats (86%), which survived 9 to 14 months following the various treatment schedules. A single i.v. injection of streptozotocin alone, 30, 40, 50, or 65 mg/kg of body weight produced adenomas of pancreatic islet cells in 8 of 9 (89%), 6 of 7 (86%), 2 of 4 (50%), and 1 of 2 rats (50%), respectively. The neoplasms were seen in all o...

The last decade has witnessed great progress on transitionmetal-catalyzed C H bond functionalization. Although many synthetically useful methods for regioselective functionalization of the C(sp) H bond of arenes and heteroarenes have been discovered, direct functionalization of C(sp) H bonds in common alkyl groups is still challenging. This challenge arises from the inert nature of most C(sp) H...