SEVERAL YEARS AGO LaDue (2) made the iiiteresting observation that soon after myocardial infarction the plasma glutamic oxalacetie tramisammase is increased, reaches a peak within a few days, and then returns to normal. This observation stimulated a new area of clinical interest ill diseases related to infarction and necrosis as manifested ill plasma enzymes changes. The source of this increase...

THIS investigation was undertaken for the purpose of studying the effect of anemia upon the hearts of rats, of determining whether cardiac hypertrophy occurs, and, if so, of studying the mechanism of hypertrophy. In spite of the widespread belief that cardiac hypertrophy does occur with anemia, Stembridge and Rigdon have indicated the lack of evidence to support many of the reported cases. Thei...

Although the milk-clotting action of papain has been recognized for many years, this property of the enzyme has received little quantitative attention. It appears to be, however, a characteristic property of the proteolytic component of this enzyme system. Various workers have brought forth evidence as to the composite nature of the papain system, which has at least two components. In the most ...

7 Davidson and Bogert, forthcoming publication. 8 Davidson and Bogert, forthcoming publication. 9 Behrend, Ann. Chem., 245, 213 (1888); Behrend and Ernert, Ibid., 258, 347 (1890). 10 Angeli, Atti. accad. Lincei, [5] 3, II, 72 (1894). 11 Johnson, Baudisch, and Hoffmann, loc. cit. 12 Levene, Bass, and Simms, J. Biol. Chem., 70, 229 (1926). 13 Behrend and Roosen, Ann. Chem., 251, 235 (1889). 14 Be...

Erythroblast denucleation in the peripheral blood was studied by electron microscopy. Blood was used from dogs anemic either by infection with Babesia canis or from injections of phenylhydrazine hydrochloride. One of the earliest stages of denucleation was the migration of nuclei to the plasmalemma. Mitochondria and coalesced vesicles, derived from the cell membrane of the erythroblast, congreg...