نتایج جستجو برای: ph sensitive drug delivery system

تعداد نتایج: 3189822  

2018
Zhongjun Cheng Xiaoliang Chen Dongliang Zhai Feiyan Gao Tingwang Guo Wenfeng Li Shilei Hao Jingou Ji Bochu Wang

BACKGROUND Nanotechnology-based drug delivery systems have been widely used for oral and systemic dosage forms delivery depending on the mucoadhesive interaction, and keratin has been applied for biomedical applications and drug delivery. However, few reports have focused on the keratin-based mucoadhesive drug delivery system and their mechanisms of mucoadhesion. Thus, the mucoadhesion controll...

2016
Yongjiu Lv Lan Hao Wenjing Hu Ya Ran Yan Bai Liangke Zhang

This study fabricated novel multifunctional pH-sensitive nanoparticles loaded into microbubbles (PNP-MB) with the combined advantages of two excellent drug delivery vehicles, namely, pH-sensitive nanoparticles and microbubbles. As an antitumor drug, resveratrol (RES) was loaded into acetylated β-cyclodextrin nanoparticles (RES-PNP). The drug-loaded nanoparticles were then encapsulated into the ...

H.G. Shivakumar N. Vishal Gupta,

   The objective of the present study is to develop and investigate the swelling behavior of pH-sensitive Superporous Hydrogel (SPH) and SPH composite (SPHC). A novel superporous hydrogel containing poly (methacrylic acid-co-acrylamide) was synthesized from methacrylic acid and acrylamide through the aqueous solution polymerization, using N,N-methylenebisacrylamide as a crosslinker and ammonium...

Journal: :Materials Today 2013

2013
Eun-Kyung Lim Warayuth Sajomsang Yuna Choi Eunji Jang Hwunjae Lee Byunghoon Kang Eunjung Kim Seungjoo Haam Jin-Suck Suh Sang Jeon Chung Yong-Min Huh

Smart drug delivery systems that are triggered by environmental conditions have been developed to enhance cancer therapeutic efficacy while limiting unwanted effects. Because cancer exhibits abnormally high local acidities compared to normal tissues (pH 7.4) due to Warburg effects, pH-sensitive systems have been researched for effective cancer therapy. Chitosan-based intelligent theragnosis nan...

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