A 57-year-old male was found to have papillary transitional cell carcinoma of the urinary bladder and underwent a tranurethral resection of the tumor. He suffered from multiple asymptomatic red papules on glans penis after 9 th intravesical therapy with Bacillus Calmette-Guerin (BCG ). His left inguinal lymph node was enlarged and tender. The skin lesions were found to be due to suppurative gra...

In duodenal ulceration the Alcian blue staining acid mucosubstances in goblet cells are reduced and the goblet cells themselves disappear. At the same time periodic acid-Schiff (PAS) staining neutral mucosubstances appear in the cells of the surface epithelium. These changes have been measured quantitatively with the help of a Vickers M86/0010 Scanning and Integrated Microdensitometer. During h...

1. Glycogen was studied in retinas of the chick (Gallus gallus), fixed in Gendre's fluid and stained by the periodic acid/Schiff method. In agreement with some of the earlier data on the subject, obtained with less suitable methods, glycogen was found in the paraboloid of accessory cones and in the characteristically shaped paraboloid of the rods. 2. Basiphilia, observable by means of the gallo...

A cytochemical study of the lysosomal enzyme beta-glucuronidase in 60 cases of acute leukaemia has shown a qualitative difference in the cytoplasmic distribution of the enzyme between blast cells of the lymphoid and myeloid cell series. This difference provides a useful additional method for cytochemical classification of cell type and is superior in this respect to the other lysosomal enzymes ...

A 26-year-old assistant nurse was referred .from the Sungei Buloh District Hospital for investigation of anaemia in December 1980. On admission, she had marked pallor and hepatosplenomegaly. Her peripheral blood showed pancytopenia with 80% of white cells being blast cells. These blast cells were rather homogeneous in size and shape, with single poorly-defined nucleolus. Cytochemical study show...

A 7-year-old Korean girl presented with an 8-month history of an erythematous hard plaque on her left hand. There was no history of trauma. On physical examination, a 1.4 0.8-cm firm plaque was observed on the ulnar surface of the left hand at the metacarpophalangeal level (Figure). Histopathologic examination showed moderately cellular fibroblasts throughout the dermis. Hematoxylineosin staini...

groups was hypertonicity of the bronchial wall, which was frequent in the asthmatics and absent in the chronic bronchitics. Mucus was scanty and viscous in the asthmatics and more abundant and watery in the chronic bronchitics. Hypersecretion of mucus occurred in both groups. In asthma the mucous hyperplasia affected chiefly the goblet cells. In chronic bronchitis the deeper bronchial glands we...

BACKGROUND Glycogen-rich carcinoma is a rare special histologic subtype of breast cancer and its incidence is estimated to be 1.4% in breast malignancies. However, its precise characteristics in cytological specimens have not yet been fully clarified. CASE Fifty-nine-year-old and 53-year-old women underwent fine-needle aspiration biopsy cytology (FNABC) of a breast tumor, confirming malignanc...

OBJECTIVE To analyse a decade-long pattern of clinical presentation of acute myeloid leukaemia patients and compare it with contemporary data. METHODS The retrospective cohort study was conducted at the National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, and comprised of medical record of acute myeloid leukaemia patients from March 2006 to October 2016. Data noted a...

Bilateral orchidectomy performed on 10- to 15-day-old Wistar rats, immediately followed by the homograft of one testis into the splenopancreatic epiploon, resulted 6 months later in leydigiomas at the site of the graft in 100% of the animals. After this latency period, the tumors continued to grow proportionately to time elapsed and were associated with both pituitary microadenomas of the aldeh...