نتایج جستجو برای: paraquat dichloride

تعداد نتایج: 5267  

2017
Yunfang Zhou Mengrou Lu Jie Weng Zhiyi Wang Fa Sun Peiwu Geng Shuanghu Wang Lufeng Hu Zhimou Gao Xianqin Wang Le Liu

In this study, we developed a gas chromatography-mass spectrometry (GC-MS)-based serum metabolomic analysis method to evaluate the effects of pirfenidone in rats with acute paraquat poisoning. The rats were divided into four groups, acute paraquat poisoning group, low pirfenidone group, high pirfenidone group, and control group. The acute paraquat poisoning group rats were given 20 mg/kg of par...

Journal: :The Biochemical journal 1993
L A Clejan A I Cederbaum

Glycerol can be oxidized to formaldehyde by microsomes in a reaction that is dependent on cytochrome P-450. An oxidant derived from the interaction of H2O2 with iron was responsible for oxidizing the glycerol, with P-450 suggested to be necessary to produce H2O2 and reduce non-haem iron. The effect of paraquat on formaldehyde production from glycerol and whether paraquat could replace P-450 in ...

2012
Sabine Leber Gert Kollenz Curt Wentrup

C(72)-Macrocyclic systems functionalized with nitroaryl and arylamino groups were synthesized from the bisdioxine diacid dichloride 1,3,5,7-tetra-tert-butyl-2,6,9-trioxabicyclo[3.3.1]nona-3,7-diene-4,8-dicarbonyl dichloride (3).

2017
Dong Ryul Ko Sung Phil Chung Je Sung You Soohyung Cho Yongjin Park Byeongjo Chun Jeongmi Moon Hyun Kim Yong Hwan Kim Hyun Jin Kim Kyung-Woo Lee SangChun Choi Junseok Park Jung Soo Park Seung Whan Kim Jeong Yeol Seo Ha Young Park Su Jin Kim Hyunggoo Kang Dae Young Hong Jung Hwa Hong

PURPOSE In Korea, registration of paraquat-containing herbicides was canceled in November 2011, and sales thereof were completely banned in November 2012. We evaluated the effect of the paraquat ban on the epidemiology and mortality of herbicide-induced poisoning. MATERIALS AND METHODS This retrospective study analyzed patients treated for herbicide poisoning at 17 emergency departments in So...

2014
Ming-wei Liu Mei-xian Su Wei Zhang Yan-qiong Wang Mei Chen Li Wang Chuan-yun Qian

BACKGROUND Exposure to paraquat results in acute lung injury. A systemic inflammatory response has been widely established as a contributor to paraquat-induced acute lung injury. Recent studies have reported that consumption of Xuebijing prevents inflammatory response-induced diseases. This study investigated whether consumption of Xuebijing protected rats against paraquat-induced acute lung in...

2012
Thomas W. Eubank Vijay K. Nandula Daniel H. Poston David R. Shaw

Greenhouse and field studies were conducted in 2007 and 2008 to investigate possible multiple-resistance of horseweed to paraquat and glyphosate, and to evaluate the effect of the addition of metribuzin to paraquat on control of paraquat-resistant horseweed. Results indicated that the GR50 (herbicide dose required to cause a 50% reduction in plant growth) value for the susceptible population S1...

Journal: :Hiroshima journal of medical sciences 1983
J Yamauchi M Yashiki I Une T Kojima H Ito S Kawachi M Ohtani

In a case of fatal paraquat poisoning, the distribution of paraquat was determined by a) the column chromatographic method developed by Tompsett, b) the ion-pairing method, c) the deproteinization method both developed by Jarvie et al, and d) the precipitation method developed by the authors. The precipitation method relies on the use of a precipitate of paraquat with Reinecke's salt to extract...

Journal: :Letters in applied microbiology 2015
E V Prazdnova V A Chistyakov M N Churilov M S Mazanko A B Bren A Volski M L Chikindas

UNLABELLED DNA protective and antioxidant activity of Bacillus amyloliquefaciens B-1895 and Bacillus subtilis KATMIRA1933 were evaluated by Escherichia coli-based Lux biosensors. Two biosensor strains of E. coli, MG1655 (pColD-lux) and MG1655 (pSoxS-lux), which react on DNA damage and superoxide-anion radical activity, were used. SOS-response and Sox-response were stimulated by addition of diox...

2015
Yeo Jin Jang Jong Hoon Won Moon Jung Back Zhicheng Fu Ji Min Jang Hae Chan Ha SeungBeom Hong Minsun Chang Dae Kyong Kim

Paraquat dichloride (N,N-dimethyl-4-4'-bipiridinium, PQ) is an extremely toxic chemical that is widely used in herbicides. PQ generates reactive oxygen species (ROS) and causes multiple organ failure. In particular, PQ has been reported to be an immunotoxic agrochemical compound. PQ was shown to decrease the number of macrophages in rats and suppress monocyte phagocytic activity in mice. Howeve...

Journal: :Indian journal of biochemistry & biophysics 2010
Ravikumar Hosamani Muralidhara

Environmental exposure to the oxidant-producing herbicide, paraquat (PQ) (1,1'-dimethyl-4,4'-bipyridinium dichloride) has long been implicated as a risk factor in Parkinson's disease (PD). PQ-induced oxidative stress has been exploited as a model to screen putative neuroprotective compounds employing Drosophila. In the present study, we investigated the prophylactic efficacy of Bacopa monnieri ...

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