PURPOSE Type 2 diabetes mellitus (T2DM) is a multifactorial disease characterized by insulin resistance. As time progresses, monotherapy often does not provide effective glycemic control, generating the need for an add-on therapy. Hence, multiple oral hypoglycemic agents formulated as a single-dose form called fixed-dose combinations (FDCs) play an essential role in glycemic control. The purpos...

Cuscuta reflexa (whole plant) and Calotropis procera (leaves) are used in folk medicine of Bangladesh to control blood sugar in patients suffering from diabetes mellitus. The hypoglycemic effects of methanol and chloroform extracts of whole plants of Cuscuta reflexa, and methanol extract of leaves of Calotropis procera were investigated in oral glucose tolerance tests in Long Evans rats and Swi...

INTRODUCTION Traditionally, insulin has been the gold standard in the management of Type 2 diabetes in pregnancy and gestational diabetes. However, insulin therapy can be inconvenient because of the needs for multiple injections, its associated cost, pain at the injection site, need for refrigeration, and skillful handling of the syringes. This has led to the exploration of oral hypoglycemic ag...

Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia. The management of the blood glucose level is a critical strategy in the control of diabetes complications. Inhibitors of carbohydrate hydrolyzing enzymes have been useful as oral hypoglycemic drugs for the control of hyperglycemia especially in patients with type II disables mellitus. The goal of the present study...

garlic (allium sativum l., alliaceae), persian shallot (allium ascalonicum l., alliaceae ) and sage (salvia officinalis l., lamiaceae) are believed to have hypoglycemic properties and have been used traditionally as antidiabetic herbal medicines in iran. in this study, diabetes was induced by subcutaneous injection of alloxan monohydrate (100 mg kg−1) to male wistar rats. antidiabetic effects of...

diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia. the management of the blood glucose level is a critical strategy in the control of diabetes complications. inhibitors of carbohydrate hydrolyzing enzymes have been useful as oral hypoglycemic drugs for the control of hyperglycemia especially in patients with type ii disables mellitus. the goal of the present study...

Methods We treated 108, 80 obese and 28 non-obese, children diagnosed as having T2DM. Among these patients, 26 obese and 23 non-obese children were assigned to pharmacological therapies during the course of diabetes. The frequency of progression to pharmacologic therapies was significantly higher in non-obese than in obese patients (82.1% vs. 32.5%, P<0.05). As to the indication for pharmacolog...

Gestational diabetes mellitus (GDM) is a serious and frequent concern in pregnancy. Worldwide, the prevalence of GDM ranges from 8 to 20%. In 5% cases, this pathology accompanied by complications such as diabetic fetopathy, preeclampsia, neonatal hypoglycemia, hyperbilirubinemia. Modern national foreign guidelines for detecting hyperglycemia during pregnancy diagnosing recommend lifestyle chang...

Diabetes is a common metabolic disease that causes cardiovascular disease. Insulin and oral hypoglycemic drugs are the treatment for diabetes, but high percentage of patients cannot use allopathic rely on natural alternative healings. Camel milk with therapeutic properties, good source vitamins C, minerals such as Mn, iron, Cu, Zn; immunoglobulins compared to cow milk. camel great substitute du...

Respiratory Syncytial Viral Infection is one of the most common viral infections in respiratory airways and more infants, younger children some adults. Although ribavirin has been used management RSV infection, many effective drugs are still under development. Also, structured based drug design using computational tools shifted paradigm discovery. The fusion core (RSV) structure crucial for its...