background & aim: oleuropein has pharmacologic properties and is the main component of olive leaves which is considered to be the most pharmacologic compounds of olive (olea europaea l.). the aim of this work was to investigate the possible using of the extract of this plant in food industry (sponge cake) in order to take advantage of its medicinal properties.experimental: ethanolic extract...

In the present study, olive leaves of eight varieties were investigated for the total phenol and flavonoid content, for the major compound and for the in vitro antioxidant properties. The different varieties showed a high content of polyphenol and flavonoid. Oleuropein was the major compound of the leaf extract for all varieties. Also, olive leaves extract exhibited a good antioxidant activity ...

Olea europaea L. leaves are an agricultural waste product with a high concentration of phenolic compounds; especially oleuropein. Oleuropein has been shown to exhibit anti-proliferative activity against a number of cancer types. However, they have not been tested against pancreatic cancer, the fifth leading cause of cancer related death in Western countries. Therefore, water, 50% ethanol and 50...

Several naturally occurring dietary polyphenols with chemopreventive or anticancer properties are topoisomerase II poisons. To identify additional phytochemicals that enhance topoisomerase II-mediated DNA cleavage, a library of 341 Mediterranean plant extracts was screened for activity against human topoisomerase IIα. An extract from Phillyrea latifolia L., a member of the olive tree family, di...

Oleuropein (OLE) is a major constituent of the olive leaf and green olives (Olea europaea). It has antioxidant and therapeutic properties and is valued as a medicinal component. The molecule is a complex phenolic compound constituted by a heterosidic ester of the elenolic acid and dihydroxy ethanol. This work concerns the determination of the inclusion complex constants between OLE and cyclodex...

background: deltamethrin (dm) is a synthetic pyrethroid insecticide that can elicit neurotoxicity, leading to apoptosis. there is accumulating evidence that oleuropein (oe) has anti-apoptotic effect. the purpose of this study was to determine the anti-apoptotic effect of oe pretreatment in the neuronal cells of cerebral cortex. methods: rats were randomly divided into four groups each containin...

Cancer comprises a collection of related diseases characterized by the existence of altered cellular pathways resulting in an abnormal tendency for uncontrolled growth. A broad spectrum, coordinated, and personalized approach focused on targeting diverse oncogenic pathways with low toxicity and economic natural compounds can provide a real benefit as a chemopreventive and/or treatment of this c...

background: oleuropein is a phenolic compound which is present in the olive leaf extract. the purpose of the present study was to investigate the neuroprotective effect of oleuropein as an antioxidant agent on the substantia nigra in aged rats. methods: twenty 18-month-old wistar rats (450-550 g) were randomly divided into control and experimental groups. the experimental group received a daily...